MCNPX Estimation of Photoneutron Dose to Eye Voxel Anthropomorphic Phantom From 18 MV Linear Accelerator.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
Ali Aa Alghamdi
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Abstract

The dose due to photoneutron contamination outside the field of irradiation can be significant when using high-energy linear accelerators. The eye is a radiation-sensitive organ, and this risk increases when high linear energy transfer neutron radiation is involved. This study aimed to provide a fast method to estimate photoneutron dose to the eye during radiotherapy. A typical high-energy linear accelerator operating at 18 MV was simulated using the Monte Carlo N-Particle Transport Code System extended version (MCNPX 2.5.0). The latest International Atomic Energy Agency photonuclear data library release was integrated into the code, accounting for the most known elements and isotopes used in typical linear accelerator construction. The photoneutron flux from a 5 × 5 cm2 field size was scored at the treatment table plane and used as a new source for estimating the absorbed dose in a high-resolution eye voxel anthropomorphic phantom. In addition, common shielding media were tested to reduce the photoneutron dose to the eye using common shielding materials. Introducing a 2 cm thickness of common neutron shielding medium reduced the total dose received in the eye voxel anthropomorphic phantom by 54%. In conclusion, individualized treatment based on photoneutron dose assessment is essential to better estimate the secondary dose inside or outside the field of irradiation.

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18 MV直线加速器对眼体素拟人化幻影的光子中子剂量MCNPX估计
当使用高能直线加速器时,辐射场外光子中子污染的剂量可能是显著的。眼睛是一个辐射敏感器官,当涉及高线性能量转移中子辐射时,这种风险增加。本研究旨在提供一种快速估计放射治疗中光子中子剂量的方法。利用蒙特卡罗n粒子输运码系统扩展版(MCNPX 2.5.0)模拟了典型的18 MV高能直线加速器。最新发布的国际原子能机构光子核数据库被整合到代码中,说明了典型线性加速器结构中使用的最已知元素和同位素。在治疗台面上记录了5 × 5 cm2场大小的光子中子通量,并将其作为高分辨率眼体素拟人模型中吸收剂量估计的新来源。此外,还测试了普通屏蔽介质对使用普通屏蔽材料降低光子中子对眼睛的剂量的影响。引入厚度为2 cm的普通中子屏蔽介质可使眼素拟人化幻影的总剂量降低54%。综上所述,基于光子中子剂量评估的个体化治疗对于更好地估计辐照场内外的二次剂量至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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