Fixation of an orthodontic anchor screw using beta-tricalcium phosphate in a screw-loosening model in rats.

IF 3 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Angle Orthodontist Pub Date : 2023-02-10 DOI:10.2319/080822-558.1

Kie Nishioka-Sakamoto, Hitoshi Hotokezaka, Yuka Hotokezaka, Yukako Nashiro, Mariko Funaki, Seigo Ohba, Noriaki Yoshida

{"title":"Fixation of an orthodontic anchor screw using beta-tricalcium phosphate in a screw-loosening model in rats.","authors":"Kie Nishioka-Sakamoto, Hitoshi Hotokezaka, Yuka Hotokezaka, Yukako Nashiro, Mariko Funaki, Seigo Ohba, Noriaki Yoshida","doi":"10.2319/080822-558.1","DOIUrl":null,"url":null,"abstract":"Objectives: To create an orthodontic anchor screw (OAS)-loosening model and to investigate whether filling the bone hole with beta-tricalcium phosphate (β-TCP) can fix the OAS against orthodontic force.Materials and methods: Bone holes with different diameters (1.6, 2.1, or 2.5 mm) were drilled in the tibias of 11-week-old male Wistar rats, and an OAS (3.0 mm in length and 1.2 mm in diameter) was inserted. After a healing period of 2 or 4 weeks, orthodontic force was applied, and the diameter of the bone hole appropriate for the loosening model was determined. Subsequently, under the loosening model, the bone hole was filled with β-TCP, orthodontic force was applied, and movement of the OAS and surrounding tissue changes were evaluated by micro-computed tomography images and histological specimen analysis.Results: The bone hole of 1.6 mm in diameter was employed as the OAS-loosening model. When β-TCP was inserted into the bone hole, the linear distance and mesial tipping angle of the OAS movement decreased markedly. Furthermore, the values of bone morphometry significantly increased with β-TCP filling.Conclusions: An OAS-loosening model was established in rats and demonstrated that the loosening OAS was stabilized by β-TCP filling through bone formation. β-TCP may be useful for fixation of a loosening OAS.","PeriodicalId":50790,"journal":{"name":"Angle Orthodontist","volume":" ","pages":""},"PeriodicalIF":3.0000,"publicationDate":"2023-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117216/pdf/i1945-7103-93-3-341.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Angle Orthodontist","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2319/080822-558.1","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}

引用次数: 0

Abstract

Objectives: To create an orthodontic anchor screw (OAS)-loosening model and to investigate whether filling the bone hole with beta-tricalcium phosphate (β-TCP) can fix the OAS against orthodontic force.

Materials and methods: Bone holes with different diameters (1.6, 2.1, or 2.5 mm) were drilled in the tibias of 11-week-old male Wistar rats, and an OAS (3.0 mm in length and 1.2 mm in diameter) was inserted. After a healing period of 2 or 4 weeks, orthodontic force was applied, and the diameter of the bone hole appropriate for the loosening model was determined. Subsequently, under the loosening model, the bone hole was filled with β-TCP, orthodontic force was applied, and movement of the OAS and surrounding tissue changes were evaluated by micro-computed tomography images and histological specimen analysis.

Results: The bone hole of 1.6 mm in diameter was employed as the OAS-loosening model. When β-TCP was inserted into the bone hole, the linear distance and mesial tipping angle of the OAS movement decreased markedly. Furthermore, the values of bone morphometry significantly increased with β-TCP filling.

Conclusions: An OAS-loosening model was established in rats and demonstrated that the loosening OAS was stabilized by β-TCP filling through bone formation. β-TCP may be useful for fixation of a loosening OAS.

查看原文本刊更多论文

在大鼠螺钉松动模型中使用 beta 磷酸三钙固定正畸固定螺钉。

目的建立正畸锚定螺钉（OAS）松动模型，并研究用β-磷酸三钙（β-TCP）填充骨孔是否能固定OAS以抵御正畸力：在 11 周大雄性 Wistar 大鼠的胫骨上钻出不同直径（1.6、2.1 或 2.5 毫米）的骨孔，然后插入 OAS（长 3.0 毫米，直径 1.2 毫米）。经过 2 或 4 周的愈合期后，施加正畸力，并确定适合松动模型的骨孔直径。随后，在松动模型下，用β-TCP填充骨孔，施加正畸力，通过微计算机断层扫描图像和组织学标本分析评估 OAS 的移动和周围组织的变化：结果：采用直径为 1.6 毫米的骨孔作为 OAS 松动模型。将β-TCP插入骨孔后，OAS运动的线性距离和中线倾角明显减小。此外，骨形态测量值随着β-TCP的填充而明显增加：结论：在大鼠体内建立了一个 OAS 松动模型，并证明通过骨形成，β-TCP 填充物可稳定松动的 OAS。β-TCP可用于固定松动的OAS。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Angle Orthodontist 医学-牙科与口腔外科

CiteScore

6.40

自引率

5.90%

发文量

审稿时长

3 months

期刊介绍： The Angle Orthodontist is the official publication of the Edward H. Angle Society of Orthodontists and is published bimonthly in January, March, May, July, September and November by The EH Angle Education and Research Foundation Inc. The Angle Orthodontist is the only major journal in orthodontics with a non-commercial, non-profit publisher -- The E. H. Angle Education and Research Foundation. We value our freedom to operate exclusively in the best interests of our readers and authors. Our website www.angle.org is completely free and open to all visitors.