Update on Toxic Neuropathies.

IF 2 4区医学 Q1 Medicine

Current Treatment Options in Neurology Pub Date : 2022-05-01 DOI:10.1007/s11940-022-00716-5

Jannik Peters, Nathan P Staff

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引用次数: 1

Abstract

Purpose of review: Toxic neuropathies are an important preventable and treatable form of peripheral neuropathy. While many forms of toxic neuropathies have been recognized for decades, an updated review is provided to increase vigilant in this area of neurology. A literature review was conducted to gather recent information about toxic neuropathies, which included the causes, clinical findings, and treatment options in these conditions.

Recent findings: Toxic neuropathies continue to cause significant morbidity throughout the world and the causative agents, particularly with regards to medications, do not appear to be diminishing. A wide variety of causes of toxic neuropathies exist, which include alcohol, industrial chemicals, biotoxins, and medications. Unfortunately, no breakthrough treatments have been developed and prevention and symptom management remain the standard of care.

Summary: A detailed medication, occupational and hobby exposure history is critical to identifying toxic neuropathies. Increased research is warranted to identify mechanisms of neurotoxic susceptibility and potential common pathomechanistic pathways for treatment across diverse toxic neuropathies.

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中毒性神经病的最新进展。

综述目的:中毒性神经病是一种重要的可预防和可治疗的周围神经病变。虽然许多形式的中毒性神经病已经被认识了几十年，但提供了一份最新的综述，以提高神经病学领域的警惕。我们进行了文献综述，以收集有关中毒性神经病的最新信息，包括病因、临床表现和治疗方案。最近的发现:在世界范围内，毒性神经病继续引起显著的发病率，而致病因子，特别是与药物有关的病原体，似乎并没有减少。引起中毒性神经病的原因多种多样，包括酒精、工业化学品、生物毒素和药物。不幸的是，没有突破性的治疗方法被开发出来，预防和症状管理仍然是标准的护理。摘要:详细的用药、职业和爱好暴露史对于确定中毒性神经病至关重要。有必要增加研究以确定神经毒性易感性的机制和潜在的共同病理机制途径，以治疗不同的毒性神经病。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Treatment Options in Neurology CLINICAL NEUROLOGY-

CiteScore

4.00

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： This journal aims to review the most important, recently published treatment option advances in the field of neurology. By presenting clear, insightful, balanced contributions by international experts, the journal intends to facilitate worldwide approaches to the treatment of neurologic conditions. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as epilepsy, headache, neurologic ophthalmology and otology, neuromuscular disorders, psychiatric manifestations of neurologic disease, and sleep disorders. Section Editors select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. We also provide commentaries from well-known neurologists, and an international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research.