Occupational exposure to polycyclic aromatic hydrocarbons in Korean adults: evaluation of urinary 1-hydroxypyrene, 2-naphthol, 1-hydroxyphenanthrene, and 2-hydroxyfluorene using Second Korean National Environmental Health Survey data.

IF 1.2 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Annals of Occupational and Environmental Medicine Pub Date : 2023-03-24 eCollection Date: 2023-01-01 DOI:10.35371/aoem.2023.35.e6

Dong Hyun Hong, Jongwon Jung, Jeong Hun Jo, Dae Hwan Kim, Ji Young Ryu

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Abstract

Background: Polycyclic aromatic hydrocarbons (PAHs) are occupational and environmental pollutants generated by the incomplete combustion of organic matter. Exposure to PAHs can occur in various occupations. In this study, we compared PAH exposure levels among occupations based on 4 urinary PAH metabolites in a Korean adult population.

Methods: The evaluation of occupational exposure to PAHs was conducted using Second Korean National Environmental Health Survey data. The occupational groups were classified based on skill types. Four urinary PAH metabolites were used to evaluate PAH exposure: 1-hydroxypyrene (1-OHP), 2-naphthol (2-NAP), 1-hydroxyphenanthrene (1-OHPHE), and 2-hydroxyfluorene (2-OHFLU). The fraction exceeding the third quartile of urinary concentration for each PAH metabolite was assessed for each occupational group. Adjusted odds ratios (ORs) for exceeding the third quartile of urinary PAH metabolite concentration were calculated for each occupational group compared to the "business, administrative, clerical, financial, and insurance" group using multiple logistic regression analyses.

Results: The "guard and security" (OR: 2.949; 95% confidence interval [CI]: 1.300-6.691), "driving and transportation" (OR: 2.487; 95% CI: 1.418-4.364), "construction and mining" (OR: 2.683; 95% CI: 1.547-4.655), and "agriculture, forestry, and fisheries" (OR: 1.973; 95% CI: 1.220-3.191) groups had significantly higher ORs for 1-OHP compared to the reference group. No group showed significantly higher ORs than the reference group for 2-NAP. The groups with significantly higher ORs for 1-OHPHE than the reference group were "cooking and food service" (OR: 2.073; 95% CI: 1.208-3.556), "driving and transportation" (OR: 1.724; 95% CI: 1.059-2.808), and "printing, wood, and craft manufacturing" (OR: 2.255; 95% CI: 1.022-4.974). The OR for 2-OHFLU was significantly higher in the "printing, wood, and craft manufacturing" group (OR: 3.109; 95% CI: 1.335-7.241) than in the reference group.

Conclusions: The types and levels of PAH exposure differed among occupational groups in a Korean adult population.

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韩国成年人职业暴露于多环芳烃的情况：利用第二次韩国全国环境健康调查数据评估尿液中的 1-羟基芘、2-萘酚、1-羟基菲和 2-羟基芴。

背景：多环芳烃（PAHs）是有机物不完全燃烧产生的职业和环境污染物。各种职业都可能接触多环芳烃。在这项研究中，我们根据韩国成年人群中尿液中的 4 种 PAH 代谢物，比较了不同职业的 PAH 暴露水平：方法：我们利用第二次韩国全国环境健康调查的数据，对多环芳烃的职业暴露进行了评估。方法：利用第二次韩国全国环境健康调查数据对职业人群多环芳烃暴露情况进行了评估，并根据技能类型对职业人群进行了分类。采用四种尿 PAH 代谢物来评估 PAH 暴露情况：1-羟基芘（1-OHP）、2-萘酚（2-NAP）、1-羟基菲（1-OHPHE）和 2-羟基芴（2-OHFLU）。对每个职业组中尿液中每种多环芳烃代谢物浓度超过第三四分位数的部分进行了评估。通过多重逻辑回归分析，计算出每个职业组与 "商业、行政、文秘、金融和保险 "组相比，尿液中 PAH 代谢物浓度超过第三四分位数的调整几率比（ORs）：与参照组相比，"警卫和保安 "组（OR：2.949；95% 置信区间[CI]：1.300-6.691）、"驾驶和运输 "组（OR：2.487；95% CI：1.418-4.364）、"建筑和采矿 "组（OR：2.683；95% CI：1.547-4.655）以及 "农业、林业和渔业 "组（OR：1.973；95% CI：1.220-3.191）的 1-OHP ORs 明显更高。没有组别显示 2-NAP 的 ORs 明显高于参照组。1-OHPHE OR 值明显高于参照组的组别是 "烹饪和食品服务"（OR：2.073；95% CI：1.208-3.556）、"驾驶和运输"（OR：1.724；95% CI：1.059-2.808）以及 "印刷、木材和工艺品制造"（OR：2.255；95% CI：1.022-4.974）。印刷、木材和工艺制造 "组的 2-OHFLU OR 值（OR：3.109；95% CI：1.335-7.241）明显高于参照组：结论：在韩国成年人群中，不同职业组的多环芳烃暴露类型和水平各不相同。

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来源期刊

Annals of Occupational and Environmental Medicine PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

1.90

自引率

0.00%

发文量

审稿时长

16 weeks

期刊介绍： Annals of Occupational and Environmental Medicine (AOEM) is an open access journal that considers original contributions relevant to occupational and environmental medicine and related fields, in the form of original articles, review articles, short letters and case reports. AOEM is aimed at clinicians and researchers working in the wide-ranging discipline of occupational and environmental medicine. Topic areas focus on, but are not limited to, interactions between work and health, covering occupational and environmental epidemiology, toxicology, hygiene, diagnosis and treatment of diseases, management, organization and policy. As the official journal of the Korean Society of Occupational and Environmental Medicine (KSOEM), members and authors based in the Republic of Korea are entitled to a discounted article-processing charge when they publish in AOEM.