Early life experiences and adult attachment in obsessive-compulsive disorder. Part 1: Relationships between demographic, clinical, and psychological factors in pharmacoresistant OCD.

IF 0.6 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM
Neuro endocrinology letters Pub Date : 2022-12-29
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引用次数: 0

Abstract

Objectives: Obsessive-compulsive disorder (OCD) has been connected to various psychosocial factors that might influence its onset and course. Developmental factors, such as parenting styles or early adverse experiences, and adult attachment have been listed as examples. However, the research on the interconnections of these factors brought mixed results. The study explores the relationship between demographic, clinical, and selected psychosocial factors and the severity of adult OCD.

Method: Eighty-seven pharmacoresistant inpatients with OCD were admitted between October 2019 and August 2022 for a 6-week cognitive behavioural therapy inpatient program in the psychotherapeutic department. The participants completed the following scales at the start of the hospitalisation: the self-report Yale-Brown Obsessive-Compulsive Scale (Y-BOCS-SR), Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI-II), Dissociative Experiences Scale (DES), Childhood Trauma Questionnaire-Short Form (CTQ-SF), PBI (Parental Bonding Instrument), ECR-R (Experiences in Close Relationships - Revised), and a demographic questionnaire. A skilled psychologist administered Mini International Neuropsychiatric Interview (MINI) to confirm the OCD diagnosis and Hamilton Anxiety Rating Scale (HAMA).

Results: OCD patients with more severe adverse childhood experiences (ACEs) showed earlier onset of the disorder and more pronounced attachment anxiety, depressive symptoms, and dissociation and subjectively rated the severity of the disorder as more severe. Physical abuse and physical neglect were related to the severity of specific OCD symptoms. Maternal care negatively correlates with clinician-rated anxiety, patient-rated depressive symptoms, and dissociation. The maternal and paternal control positively correlated with patient-rated anxiety and depression. Attachment anxiety negatively correlated with the age of onset and positively with the severity of the clinician-rated anxiety and the patient-rated anxiety, depressive symptoms, and dissociation.

Conclusions: Early adverse experiences, perceived parental styles, and adult attachment anxiety could play a significant role in the symptoms of anxiety, depression, and dissociation. The connection with the specific obsessive-compulsive symptoms is less apparent. Still, adverse childhood events and adult attachment anxiety seem to influence the age of OCD onset.

强迫症的早期生活经历与成人依恋。第一部分:耐药强迫症的人口学、临床和心理因素之间的关系。
目的:强迫症(OCD)与各种可能影响其发病和病程的社会心理因素有关。发展因素,如父母教养方式或早期不良经历,以及成人依恋都被列为例子。然而,对这些因素之间相互关系的研究带来了不同的结果。该研究探讨了人口统计学、临床和选择的社会心理因素与成人强迫症严重程度之间的关系。方法:2019年10月至2022年8月,87例耐药强迫症住院患者在心理治疗科接受为期6周的认知行为治疗。参与者在入院前完成了以下量表:耶鲁-布朗强迫症自述量表(Y-BOCS-SR)、贝克焦虑量表(BAI)、贝克抑郁量表(BDI-II)、分离体验量表(DES)、童年创伤问卷-简表(CTQ-SF)、PBI(父母联系工具)、ECR-R(亲密关系经历-修订)和人口统计问卷。一位熟练的心理学家通过Mini国际神经精神病学访谈(Mini)来确认强迫症的诊断和汉密尔顿焦虑评定量表(HAMA)。结果:童年不良经历越严重的强迫症患者,其发病时间越早,依恋焦虑、抑郁症状、分离症状越明显,主观上对强迫症的严重程度评价越重。身体虐待和身体忽视与特定强迫症症状的严重程度有关。产妇护理与临床评定的焦虑、患者评定的抑郁症状和分离呈负相关。母亲和父亲的控制与患者评价的焦虑和抑郁呈正相关。依恋焦虑与发病年龄呈负相关,与临床评定的焦虑、患者评定的焦虑、抑郁症状和分离的严重程度呈正相关。结论:早期不良经历、感知父母风格和成人依恋焦虑可能在焦虑、抑郁和分离症状中起重要作用。与特定的强迫症症状的联系就不那么明显了。然而,童年时期的不良事件和成年后的依恋焦虑似乎会影响强迫症发病的年龄。
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来源期刊
Neuro endocrinology letters
Neuro endocrinology letters 医学-内分泌学与代谢
CiteScore
1.00
自引率
14.30%
发文量
24
审稿时长
6 months
期刊介绍: Neuroendocrinology Letters is an international, peer-reviewed interdisciplinary journal covering the fields of Neuroendocrinology, Neuroscience, Neurophysiology, Neuropsychopharmacology, Psycho­neu­ro­immunology, Reproductive Medicine, Chro­no­biology, Human Ethology and re­lated fields for RAPID publication of Original Papers, Review Articles, State-of-the-art, Clinical Reports and other contributions from all the fields covered by Neuroendocrinology Letters. Papers from both basic research (methodology, molecular and cellular biology, anatomy, histology, biology, embryology, teratology, normal and pathological physiology, biophysics, pharmacology, pathology and experimental pathology, biochemistry, neurochemistry, enzymology, chronobiology, receptor studies, endocrinology, immunology and neuroimmunology, animal phy­siology, animal breeding and ethology, human ethology, psychology and others) and from clinical research (neurology, psychiatry and child psychiatry, obstetrics and gynecology, pediatrics, endocrinology, immunology, cardiovascular studies, internal medicine, oncology and others) will be considered. The Journal publishes Original papers and Review Articles. Brief reports, Special Communications, proved they are based on adequate experimental evidence, Clinical Studies, Case Reports, Commentaries, Discussions, Letters to the Editor (correspondence column), Book Reviews, Congress Reports and other categories of articles (philosophy, art, social issues, medical and health policies, biomedical history, etc.) will be taken under consideration.
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