Systematic sequencing of imported cases leads to detection of SARS-CoV-2 B.1.1.529 (Omicron) variant in central Viet Nam.

IF 1 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Western Pacific Surveillance and Response Pub Date : 2022-10-01 DOI:10.5365/wpsar.2022.13.4.977

Do Thai Hung, Nguyen Bao Trieu, Do Thi Thu Thuy, Allison Olmsted, Trinh Hoang Long, Nguyen Duc Duy, Huynh Kim Mai, Bui Thi Thu Hien, Nguyen Van Van, Tran Van Kiem, Vo Thi Thuy Trang, Nguyen Truong Duy, Ton That Thanh, Huynh Van Dong, Philip Gould, Matthew Moore

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Abstract

As authorities braced for the arrival of the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), infrastructure investments and government directives prompted action in central Viet Nam to establish capacity for genomic surveillance sequencing. From 17 November 2021 to 7 January 2022, the Pasteur Institute in Nha Trang sequenced 162 specimens from 98 150 confirmed SARS-CoV-2 cases in the region collected from 8 November to 31 December 2021. Of these, all 127 domestic cases were identified as the B.1.617.2 (Delta) variant, whereas 92% (32/35) of imported cases were identified as the B.1.1.529 (Omicron) variant, all among international flight passengers. Patients were successfully isolated, enabling health-care workers to prepare for additional cases. Most (78%) of the 32 Omicron cases were fully vaccinated, suggesting continued importance of public health and social measures to control the spread of new variants.

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对输入病例的系统测序导致在越南中部发现SARS-CoV-2 B.1.1.529 (Omicron)变体。

在当局准备迎接严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)的欧米克隆变种到来之际，基础设施投资和政府指令促使越南中部采取行动，建立基因组监测测序能力。2021年11月17日至2022年1月7日，芽庄巴斯德研究所对该地区从2021年11月8日至12月31日收集的98150例确诊SARS-CoV-2病例中的162份标本进行了测序。其中，所有127例国内病例被确定为B.1.617.2 (Delta)变体，而92%(32/35)的输入病例被确定为B.1.1.529 (Omicron)变体，均为国际航班乘客。病人被成功隔离，使保健工作者能够为更多病例做好准备。32例Omicron病例中，大多数(78%)完全接种了疫苗，这表明公共卫生和社会措施对控制新变种的传播仍然很重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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