Extracranial Microvascular Complications of Moyamoya Disease Leading to Left Ventricular Systolic Dysfunction.

Sohiub N Assaf, Abdallah N Assaf, Muaz N Assaf, John Taylor, Justin M Adam, Justin Harrell, Jeffery Johnson
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Abstract

Moyamoya disease (MMD) was first used as a descriptor for a steno-occlusive process that affects primarily the internal carotid arteries (ICA) in a bilateral fashion in 1969. Characterized by recurrent ischemic events in the developing brains of young patients, the process is one that often decimates the quality of life of affected individuals. The vascular changes in MMD have been demonstrated to occur in an extracranial manner, thus it is logical to assume that the same steno-occlusive mechanism could induce dysfunction and ischemia in other organ systems. Our case presents a patient with MMD with cardiac manifestations that we suspect may be related to extracranial manifestations of MMD.

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烟雾病致左心室收缩功能障碍的颅外微血管并发症。
烟雾病(MMD)于1969年首次被用于描述主要影响双侧颈内动脉(ICA)的狭窄闭塞过程。其特点是在年轻患者的大脑发育过程中反复发生缺血性事件,这一过程往往会严重影响患者的生活质量。烟雾病的血管改变已被证明发生在颅外方式,因此我们可以合理地假设相同的狭窄闭塞机制可以诱导其他器官系统的功能障碍和缺血。我们的病例是一位有心脏表现的烟雾病患者,我们怀疑这可能与烟雾病的颅外表现有关。
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