Histopathological Profile of Central Nervous System Tumors in a Peripheral Tertiary Care Centre of West Bengal.

Abstract

Introduction  Central nervous system (CNS) tumor incidence is very low in comparison to other organ neoplasm. Recent increase in the incidence may be due to exposure of the population to various risk factors, genetic mutation, or improved diagnosis with advancement in diagnostic modalities. This study aims to observe the histopathological spectrum of CNS tumors with their clinical profile and basic demography at a single center in a peripheral region in West Bengal. Material and Methods  A retrospective study was conducted in the department of pathology, Gouridevi Institute of Medical Sciences and Hospital (GIMSH), Durgapur, West Bengal, over a period of 2 years from October 2018 to September 2020 on CNS tumors. Basic demographic data, tumor site, and histopathological profile were obtained from medical records and further analyzed and graded according to the World Health Organization (WHO) classification. Result  Among 42 cases of CNS tumors, 29 cases were from different regions of the brain and 13 cases were from the spinal cord, with a male to female ratio (1.21:1); the commonest age group was the sixth decade and most common tumor was meningioma, followed by astrocytic tumors. Conclusion  The present study helps provide information regarding the burden of disease in our area. Despite the use of modern imaging techniques that help in the provisional diagnosis of disease, histological examination is the gold standard in diagnosis of varied types.