The value of contrast-enhanced ultrasound in the diagnosis of BI-RADS-US 4a lesions less than 2 cm in diameter.

IF 2.1 4区 医学 Q3 HEMATOLOGY
Mei-Qin Yu, Li-Li Zhang, Li-Ping Jiang, Ai-Yun Zhou
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引用次数: 2

Abstract

Background: Breast cancer is the most common malignant tumor in women. Early diagnosis of benign and malignant breast tumors is of great significance.

Objective: To retrospectively analyze the value of contrast-enhanced ultrasonography (CEUS) in the diagnosis of Breast Imaging-Reporting and Data System (BI-RADS) 4a breast lesions less than 2 cm in diameter.

Methods: CEUS was performed for 143 breast masses less than 2 cm in diameter that were diagnosed as BI-RADS 4a by ultrasound and reclassified. Considering pathological diagnosis as the gold standard, the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of reclassified lesions after CEUS for the diagnosis of benign and malignant masses were analyzed.

Results: BI-RADS 4a breast masses with a diameter less than 2 cm (n = 143) were confirmed by pathology; 103 and 40 were classified as benign and malignant, respectively. The sensitivity, specificity, PPV, and NPV of CEUS for the diagnosis were 90%, 86%, 72%, and 95%, respectively. The area under the receiver operating characteristic (ROC) curve of CEUS for the diagnosis of benign and malignant tumors after CEUS was 0.904.

Conclusion: CEUS can help to improve the diagnostic accuracy of BI-RADS 4a masses with a diameter less than 2 cm.

超声造影对直径小于2cm的BI-RADS-US 4a病变的诊断价值
背景:乳腺癌是女性最常见的恶性肿瘤。早期诊断乳腺良恶性肿瘤具有重要意义。目的:回顾性分析超声造影(CEUS)对乳腺影像报告与数据系统(BI-RADS) 4a型乳腺直径小于2cm病变的诊断价值。方法:对143例直径小于2 cm的乳腺肿块行超声造影,超声诊断为BI-RADS 4a并重新分类。以病理诊断为金标准,分析超声造影后重新分类病变对良恶性肿块诊断的敏感性、特异性、阳性预测值(PPV)、阴性预测值(NPV)。结果:病理证实BI-RADS 4a乳腺肿块,直径小于2 cm (n = 143);103例为良性,40例为恶性。超声造影诊断的敏感性、特异性、PPV和NPV分别为90%、86%、72%和95%。超声造影后诊断良恶性肿瘤的受试者工作特征曲线下面积为0.904。结论:超声造影有助于提高直径小于2 cm的BI-RADS 4a肿块的诊断准确性。
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来源期刊
CiteScore
4.30
自引率
33.30%
发文量
170
期刊介绍: Clinical Hemorheology and Microcirculation, a peer-reviewed international scientific journal, serves as an aid to understanding the flow properties of blood and the relationship to normal and abnormal physiology. The rapidly expanding science of hemorheology concerns blood, its components and the blood vessels with which blood interacts. It includes perihemorheology, i.e., the rheology of fluid and structures in the perivascular and interstitial spaces as well as the lymphatic system. The clinical aspects include pathogenesis, symptomatology and diagnostic methods, and the fields of prophylaxis and therapy in all branches of medicine and surgery, pharmacology and drug research. The endeavour of the Editors-in-Chief and publishers of Clinical Hemorheology and Microcirculation is to bring together contributions from those working in various fields related to blood flow all over the world. The editors of Clinical Hemorheology and Microcirculation are from those countries in Europe, Asia, Australia and America where appreciable work in clinical hemorheology and microcirculation is being carried out. Each editor takes responsibility to decide on the acceptance of a manuscript. He is required to have the manuscript appraised by two referees and may be one of them himself. The executive editorial office, to which the manuscripts have been submitted, is responsible for rapid handling of the reviewing process. Clinical Hemorheology and Microcirculation accepts original papers, brief communications, mini-reports and letters to the Editors-in-Chief. Review articles, providing general views and new insights into related subjects, are regularly invited by the Editors-in-Chief. Proceedings of international and national conferences on clinical hemorheology (in original form or as abstracts) complete the range of editorial features.
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