Prevalence, Incidence and Factors Associated with Diabetic Foot in People with Type 2 Diabetes: Systematic Review with Meta-Analysis.

IF 2.4 Q3 ENDOCRINOLOGY & METABOLISM

Current diabetes reviews Pub Date : 2024-01-01 DOI:10.2174/1573399819666230407093450

Maria de Jesus Nascimento de Aquino, Ana Célia Caetano de Souza, José Wicto Pereira Borges, Francisca Diana da Silva Negreiros, Marilia de Sousa Gonçalves, Polyanna Maria Oliveira Martins, Thereza Maria Magalhães Moreira

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引用次数: 0

Abstract

Background: Diabetic Foot is a severe chronic complication of diabetes and an important factor in the morbidity of diabetic people, resulting in high health costs and increased risk of death.

Objective: To analyze the incidence, prevalence, and risk factors associated with diabetic foot in people with type 2 Diabetes Mellitus.

Method: Systematic literature review. Searches in MedLine via PubMed, LILACS, Web of Science, Scopus CINAHL, and Cochrane Library databases were performed. Inclusion of 52 studies. The R program, Metan packages, was used to calculate the meta-analysis. Given the heterogeneity of studies, the random effect was used to calculate the meta-analysis of risk factors.

Results: The meta-analysis showed that the prevalence of diabetic foot was 14% in a hospital setting and 5% in a community setting. The overall prevalence and incidence were 9% and 4%, respectively. Significant risk factors included time of DM (odds ratio [OR] =1.46, confidence interval [CI], 0.36-2.57, P = 0.009), smoking (OR = 1.46, CI, 1.16 -1.85, P< .001), glycated hemoglobin (OR = 0.96, CI, 0.50; 1.42, P< .001), peripheral arterial disease (OR = 3.38, CI, 2.07; 5.53, P < .001) and peripheral neuropathy (OR = 5.88, CI, 2.39-14.45, P<.001).

Conclusion: Multidisciplinary monitoring, educational strategies, periodic foot examination for alterations, and early identification of risk factors are essential to prevent ulceration and reduce the disease burden.

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2 型糖尿病患者糖尿病足的患病率、发病率及相关因素：系统回顾与元分析》。

背景：糖尿病足是一种严重的慢性并发症，也是糖尿病患者发病率的重要因素：糖尿病足是糖尿病的一种严重慢性并发症，也是糖尿病患者发病率的一个重要因素，会导致高昂的医疗费用和死亡风险的增加：分析 2 型糖尿病患者糖尿病足的发病率、流行率和相关风险因素：方法：系统文献综述。通过 PubMed、LILACS、Web of Science、Scopus CINAHL 和 Cochrane Library 数据库对 MedLine 进行检索。纳入 52 项研究。使用 R 程序 Metan 软件包进行荟萃分析计算。鉴于研究的异质性，采用随机效应计算风险因素的荟萃分析：荟萃分析表明，糖尿病足的患病率在医院环境中为 14%，在社区环境中为 5%。总体患病率和发病率分别为 9% 和 4%。重要的风险因素包括：患 DM 的时间（几率比 [OR] =1.46，置信区间 [CI]，0.36-2.57，P = 0.009）、吸烟（OR = 1.46，CI，1.16-1.85，P< .001）、糖化血红蛋白（OR = 0.96，CI，0.50；1.42，P< .001）、外周动脉疾病（OR = 3.38，CI，2.07；5.53，P< .001）和周围神经病变（OR = 5.88，CI，2.39-14.45，PC结论：多学科监测、教育策略、定期检查足部变化以及早期识别风险因素对于预防溃疡和减轻疾病负担至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current diabetes reviews ENDOCRINOLOGY & METABOLISM-

CiteScore

6.30

自引率

0.00%

发文量

158

期刊介绍： Current Diabetes Reviews publishes frontier reviews on all the latest advances on diabetes and its related areas e.g. pharmacology, pathogenesis, complications, epidemiology, clinical care, and therapy. The journal"s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians who are involved in the field of diabetes.