Single-Center Retrospective Analysis of Acute Type A Aortic Dissection Outcome and Reoperation Focusing on Extended Versus Limited Initial Repair.

IF 0.7 4区 医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
Mohamed Elbayomi, Michael Weyand, Presheet Pathare, Ehab Nooh, Frank Harig
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引用次数: 0

Abstract

Background: The optimal management strategy for acute aortic type A dissection remains controversial. Whether a limited primary (index) repair would increase the need for late aortic reintervention is still an open debate.

Methods: A total of 393 consecutive adult patients with acute type A aortic dissection who underwent cardiac surgery were analyzed. Our research hypothesis was whether limited aortic index repair (i.e., isolated aorta ascending replacement without an open distal anastomosis with and without a concomitant aortic valve replacement, including hemiarch replacement procedure) is associated with a higher incidence of late aortic reoperation compared with extended repair (i.e., any other surgical procedure that goes beyond that limited approach).

Results: Type of the initial repair had no statically significant relationship with in-hospital mortality with a P-value of 0.12, however in multivariable analysis, cross-clamp time had a statistically significant relation with mortality (P = 0.4). From the patients who survived until discharge (N = 311), 40 patients needed a reoperation on the aorta; the mean interval until reoperation was 4.5 years. The relationship between the type of the initial repair and the need for reoperation didn't reach a statically significant value (P = 0.9). In-hospitable mortality after the second operation was 10% (N = 4).

Conclusion: We reached two conclusions. 1) An extended prophylactic repair in the initial operation of an acute type A aortic dissection might not lead to a lower incidence of reoperations on the aorta and could increase in-hospital mortality by increasing cross-clamp time, and 2) Reoperation on the aorta could be done safely with acceptable mortality outcomes.

急性A型主动脉夹层结局和再手术的单中心回顾性分析,重点是延长与有限的初始修复。
背景:急性A型主动脉夹层的最佳治疗策略仍存在争议。有限的初级(指数)修复是否会增加晚期主动脉再介入治疗的需要仍然是一个公开的争论。方法:对393例连续行心脏手术的成人急性A型主动脉夹层患者进行分析。我们的研究假设是,与扩展修复(即任何其他超出该有限方法的外科手术)相比,有限主动脉指数修复(即,不进行开放远端吻合的孤立主动脉上升置换术,并伴有或不伴有主动脉瓣置换术,包括血腔置换术)是否与晚期主动脉再手术的更高发生率相关。结果:初始修复类型与住院死亡率无统计学意义(P值为0.12),但在多变量分析中,交叉夹持时间与死亡率有统计学意义(P = 0.4)。在存活至出院的患者中(N = 311),有40例患者需要再次进行主动脉手术;再手术的平均时间间隔为4.5年。初次修复的类型与再次手术的需要之间的关系没有达到统计学意义(P = 0.9)。第二次手术后的不适宜居住死亡率为10% (N = 4)。结论:我们得出两个结论。1)急性A型主动脉夹层初次手术延长预防性修复期可能不会降低主动脉再次手术的发生率,反而会增加交叉夹持时间,增加住院死亡率;2)主动脉再次手术可以安全进行,死亡率可接受。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Heart Surgery Forum
Heart Surgery Forum 医学-外科
CiteScore
1.20
自引率
16.70%
发文量
130
审稿时长
6-12 weeks
期刊介绍: The Heart Surgery Forum® is an international peer-reviewed, open access journal seeking original investigative and clinical work on any subject germane to the science or practice of modern cardiac care. The HSF publishes original scientific reports, collective reviews, case reports, editorials, and letters to the editor. New manuscripts are reviewed by reviewers for originality, content, relevancy and adherence to scientific principles in a double-blind process. The HSF features a streamlined submission and peer review process with an anticipated completion time of 30 to 60 days from the date of receipt of the original manuscript. Authors are encouraged to submit full color images and video that will be included in the web version of the journal at no charge.
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