Prevalence of Coronary Artery Disease in Patients Undergoing Valvular Heart Surgery.

IF 0.7 4区医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Heart Surgery Forum Pub Date : 2023-03-03 DOI:10.1532/hsf.5331

Changwei Ren, Jianbo Yu, Jinwei Zhang, Shengwei Wang, Enjun Zhu, Hongchang Guo, Dingce Sun, Bing Tang, Hao Cui, Yongqiang Lai

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引用次数: 1

Abstract

Background: The risk of coronary artery disease (CAD) in different valve dysfunction has been unclear.

Methods: We reviewed patients, who underwent valve heart surgery and coronary angiography from 2008 to 2021, at our center.

Results: A total of 7,932 patients were included in the present study, and 1,332 (16.8%) had CAD. The mean age of the study cohort was 60.5±7.9 years, and 4,206 (53.0%) were male. CAD was 21.4% in aortic disease, 16.2% in mitral valve disease, 11.8% in isolated tricuspid valve disease, and 13.0% in combined aortic and mitral valve disease. Patients with aortic stenosis were older than those with regurgitation (63.6±7.4 years vs. 59.5±8.2 years, P < 0.001), and the CAD risks also were higher (28.0% vs. 19.2%, P < 0.001). The age difference was minimal (60.6±8.2 years vs. 59.5±6.7 years, P = 0.002) between patients with mitral valve regurgitation and stenosis, but the risks of CAD were twice high in regurgitation (20.2% vs. 10.5%, P < 0.001). When the type of valve impairment was not considered, non-rheumatic etiology, advanced age, male sex, hypertension, and diabetes were independent predictors of CAD.

Conclusion: In patients undergoing valve surgery, the prevalence of CAD was influenced by conventional risk factors. Importantly, CAD also was associated with the type and etiology of valve diseases.

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心脏瓣膜手术患者冠状动脉疾病的患病率

背景:不同瓣膜功能障碍的冠状动脉疾病(CAD)风险尚不清楚。方法:我们回顾了2008年至2021年在我们中心接受心脏瓣膜手术和冠状动脉造影的患者。结果:本研究共纳入7932例患者，其中1332例(16.8%)患有CAD。研究队列的平均年龄为60.5±7.9岁，男性4206例(53.0%)。主动脉疾病为21.4%，二尖瓣疾病为16.2%，孤立三尖瓣疾病为11.8%，主动脉和二尖瓣合并疾病为13.0%。主动脉瓣狭窄患者比反流患者年龄更大(63.6±7.4岁比59.5±8.2岁，P < 0.001)，冠心病风险也更高(28.0%比19.2%，P < 0.001)。二尖瓣返流和狭窄患者的年龄差异很小(60.6±8.2岁vs 59.5±6.7岁，P = 0.002)，但返流患者的冠心病风险是其两倍(20.2% vs 10.5%， P < 0.001)。当不考虑瓣膜损害类型时，非风湿病病因、高龄、男性、高血压和糖尿病是CAD的独立预测因素。结论:在瓣膜手术患者中，冠心病的患病率受常规危险因素的影响。重要的是，CAD还与瓣膜疾病的类型和病因有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Heart Surgery Forum 医学-外科

CiteScore

1.20

自引率

16.70%

发文量

130

审稿时长

6-12 weeks

期刊介绍： The Heart Surgery Forum® is an international peer-reviewed, open access journal seeking original investigative and clinical work on any subject germane to the science or practice of modern cardiac care. The HSF publishes original scientific reports, collective reviews, case reports, editorials, and letters to the editor. New manuscripts are reviewed by reviewers for originality, content, relevancy and adherence to scientific principles in a double-blind process. The HSF features a streamlined submission and peer review process with an anticipated completion time of 30 to 60 days from the date of receipt of the original manuscript. Authors are encouraged to submit full color images and video that will be included in the web version of the journal at no charge.