Correlates of Gait Speed Among Older Adults From 6 Countries: Findings From the COSMIC Collaboration.

IF 4.3 2区 医学 Q1 GERIATRICS & GERONTOLOGY
Briana N Sprague, Xiaonan Zhu, Andrea L Rosso, Joe Verghese, Kim Delbaere, Darren M Lipnicki, Perminder S Sachdev, Tze Pin Ng, Xinyi Gwee, Keng Bee Yap, Ki-Woong Kim, Ji Won Han, Dae Jong Oh, Kenji Narazaki, Tao Chen, Sanmei Chen, Henry Brodaty, Katya Numbers, Nicole A Kochan, Richard W Walker, Stella-Maria Paddick, Oye Gureje, Akin Ojagbemi, Toyin Bello, Caterina Rosano
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Abstract

Background: Few studies have compared gait speed and its correlates among different ethnogeographic regions. The goals of this study were to describe usual and rapid gait speed, and identify their correlates across Australian, Asian, and African countries.

Methods: We used data from 6 population-based cohorts of adults aged 65+ from 6 countries and 3 continents (N = 6 472), with samples ranging from 231 to 1 913. All cohorts are members of the Cohort Studies of Memory in an International Consortium collaboration. We investigated whether clinical (body mass index [BMI], hypertension, stroke, apolipoprotein status), psychological (cognition, mood, general health), and behavioral factors (smoking, drinking, physical activity) correlated with usual (N = 4 cohorts) and rapid gait speed (N = 3 cohorts) similarly across cohorts. Regression models were controlled for age, sex, and education, and were sex-stratified.

Results: Age- and sex-standardized usual gait speed means ranged from 0.61 to 1.06 m/s and rapid gait speed means ranged from 1.16 to 1.64 m/s. Lower BMI and better cognitive function consistently correlated with faster gait speed in all cohorts. Less consistently, not having hypertension and greater physical activity engagement were associated with faster gait speed. Associations with mood, smoking, and drinking were largely nonsignificant. These patterns were not attenuated by demographics. There was limited evidence that the associations differed by sex, except physical activity, where the greater intensity was associated with usual gait among men but not women.

Conclusions: This study is among the first to describe the usual and rapid gait speeds across older adults in Africa, Asia, and Australia.

来自6个国家的老年人步态速度的相关性:来自COSMIC合作的发现。
背景:很少有研究比较不同人种地理区域的步态速度及其相关因素。这项研究的目的是描述通常和快速的步态速度,并确定它们在澳大利亚、亚洲和非洲国家的相关性。方法:我们使用了来自6个国家和3大洲的6个以人群为基础的65岁以上成年人队列(N = 6 472)的数据,样本范围为231至1913。所有的队列都是国际联盟合作的记忆队列研究的成员。我们调查了临床(体重指数[BMI],高血压,中风,载脂蛋白状态),心理(认知,情绪,一般健康)和行为因素(吸烟,饮酒,体育活动)是否与正常(N = 4队列)和快速步态速度(N = 3队列)相似。回归模型控制了年龄、性别和教育程度,并按性别分层。结果:年龄和性别标准化的通常步态速度平均值为0.61 ~ 1.06 m/s,快速步态速度平均值为1.16 ~ 1.64 m/s。在所有队列中,较低的BMI和较好的认知功能始终与较快的步态速度相关。不太一致的是,没有高血压和更多的体育活动与更快的步态速度有关。与情绪、吸烟和饮酒的关联在很大程度上不显著。这些模式并没有因为人口统计而减弱。有有限的证据表明,这种联系因性别而异,除了体力活动,在男性中,更大的强度与正常的步态有关,而在女性中则没有。结论:这项研究是第一个描述非洲、亚洲和澳大利亚老年人通常和快速步态速度的研究之一。
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来源期刊
CiteScore
10.00
自引率
5.90%
发文量
233
审稿时长
3-8 weeks
期刊介绍: Publishes articles representing the full range of medical sciences pertaining to aging. Appropriate areas include, but are not limited to, basic medical science, clinical epidemiology, clinical research, and health services research for professions such as medicine, dentistry, allied health sciences, and nursing. It publishes articles on research pertinent to human biology and disease.
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