Oncological outcomes of elective versus emergency surgery for colon cancer: A tertiary academic center experience.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-09-01 DOI:10.4103/sjg.sjg_31_23

Thamer A Bin Traiki, Sulaiman A AlShammari, Razan N AlRabah, Amirah M AlZahrani, Saud T Alshenaifi, Noura S Alhassan, Maha-Hamadien Abdulla, Ahmad M Zubaidi, Omar A Al-Obeed, Khayal A Alkhayal

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Abstract

Background: In this study, we aimed to identify the oncological outcomes in colon cancer patients who underwent elective versus emergency curative resection.

Methods: All patients who underwent curative resection for colon cancer between July 2015 and December 2019 were retrospectively reviewed and analyzed. Patients were divided into two groups based on the presentation into elective and emergency groups.

Results: A total of 215 patients with colon cancer were admitted and underwent curative surgical resection. Of those, 145 patients (67.4%) were elective cases, and 70 (32.5%) were emergency cases. Family history of malignancy was positive in 44 patients (20.5%) and significantly more common in the emergency group (P = 0.016). The emergency group had higher T and TNM stages (P = 0.001). The 3-year survival rate was 60.9% and significantly less in the emergency group (P = 0.026). The mean duration from surgery to recurrence, 3-year disease-free survival, and overall survival were 1.19, 2.81, and 3.11, respectively.

Conclusion: Elective group was associated with better 3-year survival, longer overall, and 3-year disease-free survival compared to the emergency group. The disease recurrence rate was comparable in both groups, mainly in the first two years after curative resection.

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癌症择期手术与急诊手术的肿瘤结果：三级学术中心经验。

背景：在这项研究中，我们旨在确定癌症患者接受选择性和紧急治疗性切除的肿瘤结果。方法：回顾性分析2015年7月至2019年12月期间所有接受癌症根治性切除术的患者。根据表现将患者分为两组，分别为选择性组和急诊组。结果：共有215例癌症患者入院接受治疗性手术切除。其中145例（67.4%）为择期病例，70例（32.5%）为急诊病例。44名患者（20.5%）有恶性肿瘤家族史，急诊组更常见（P=0.016）。急诊组有较高的T和TNM分期（P=0.001）。3年生存率为60.9%，急诊组明显更低（P=0.026）。从手术到复发的平均持续时间、3年无病生存率和总生存率分别为1.19、2.81、，和3.11。结论：与急诊组相比，选择性组的3年生存率更好，总体生存期更长，3年无病生存期更长。两组的疾病复发率相当，主要发生在根治性切除后的前两年。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.