Insertion of an intrauterine contraceptive device after induced or spontaneous abortion: a review of the evidence

Nancy L Stanwood , David A Grimes , Kenneth F Schulz
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Abstract

Objective Assess the safety and efficacy of intrauterine contraceptive device (IUCD) insertion immediately after induced or spontaneous abortion.

Design Systematic search for randomised trials that had at least one treatment arm that involved IUCD insertion immediately after an induced or spontaneous miscarriage using Medline, Popline, EMBASE, and review articles supplemented by correspondence with investigators.

Population Women of any age or gravidity who had an IUCD inserted immediately after evacuation for spontaneous or induced abortion.

Methods Articles were abstracted and the raw data from tables were analysed with RevMan 3.1 software. We focused on Tietze-Potter gross life table probabilities with denominators of person-time of exposure.

Main outcome measures Rates of perforation, expulsion, pelvic inflammatory disease, contraceptive failure, and method continuation.

Results Complication rates for immediate post-abortal IUCD insertion were low. Perforation was rare with a rate of approximately one per 1000 insertions. One year gross cumulative expulsion rates ranged from 1.8% to 12.6%, pregnancy rates from 0.6% to 2.1%, and continuation rates from 54% to 90%. The net discontinuation rate due to pelvic inflammatory disease was low, ranging from 0.0 to 0.8 per 100 women at one year. Increasing gestational age at insertion was associated with increased expulsion rates.

Conclusions Post-abortal IUCD insertion is safe and effective. The risks of perforation, expulsion, pelvic inflammatory disease and contraceptive failure were low and similar to those reported for interval insertion. Second trimester gestational age is associated with an increased risk of expulsion. Immediate insertion may have a higher expulsion rate than delayed insertion. However, these risks may be outweighed by the benefit of immediate contraception.

人工流产或自然流产后插入宫内避孕器:证据综述
目的评价人工流产或自然流产后立即置入宫内节育器的安全性和有效性。使用Medline、Popline、EMBASE系统搜索至少有一个治疗组涉及在诱导流产或自然流产后立即插入IUCD的随机试验,并通过与研究者的通信补充综述文章。人口自然流产或人工流产后立即植入宫内节育器的任何年龄或妊娠的妇女。方法采用RevMan 3.1软件对文献进行摘要整理,对表格中的原始数据进行分析。我们着重于Tietze-Potter总生命表概率与个人暴露时间的分母。主要观察指标:穿孔、排出、盆腔炎、避孕失败和避孕方法继续率。结果宫内节育器即刻植入术并发症发生率低。穿孔是罕见的,发生率约为千分之一。一年累计退学率从1.8%到12.6%不等,怀孕率从0.6%到2.1%不等,继续退学率从54%到90%不等。盆腔炎导致的净停药率很低,一年内每100名妇女的停药率在0.0至0.8之间。插入时胎龄增加与排出率增加有关。结论宫内节育器植入术安全、有效。穿孔、排出、盆腔炎和避孕失败的风险较低,与间隔插入的报道相似。妊娠中期胎龄与排出风险增加有关。立即插入可能比延迟插入具有更高的排出率。然而,这些风险可能会被立即避孕的好处所抵消。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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