Xin Liang, Fei Guo, Xiaoce Cai, Jiao Wang, Jiale Chen, Li Liu, Yan Chen, Fang Liu, Yuhua Du, Lei Li, Xin Li
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引用次数: 0
Abstract
Background: We discovered that vitiligo was associated with sexual dysfunction in clinical diagnosis and treatment; however, no further analysis had been performed due to a lack of data.
Objective: This study aimed to clarify the relationship between vitiligo and sexual dysfunction.
Methods: We searched six databases (PubMed, Embase, Cochrane, China National Knowledge Infrastructure, China Science and Technology Journal, and Wanfang Data Knowledge Service Platform) for nearly 40 years.
Results: According to the search strategy, 91 relevant studies were retrieved, of which 4 were included in the analysis. The Arizona Sexual Experience Scale (ASEX) score (mean difference [MD] 4.96, 95% confidence interval [CI] 2.78-7.13, p < 0.00001) was higher in the vitiligo group than in the control group. The Arabic version of the Female Sexual Function Index (AVFSFI) score (mean difference [MD] - 3.40, 95% confidence interval [CI] - 5.49 to -1.31, p = 0.001) was lower in the vitiligo group than in the control group.
Conclusions: Patients with vitiligo were found to be at greater risk of sexual dysfunction. Moreover, the association between vitiligo and sexual dysfunction was stronger in women than in men.Key MessagesPatients with vitiligo were found to be at greater risk of sexual dysfunction.The association between vitiligo and sexual dysfunction was stronger in women than in men.
背景:我们在临床诊断和治疗中发现白癜风与性功能障碍有关;然而,由于缺乏数据,没有进行进一步的分析。目的:阐明白癜风与性功能障碍的关系。方法:检索PubMed、Embase、Cochrane、China National Knowledge Infrastructure、China Science and Technology Journal和万方数据知识服务平台6个数据库,检索近40个 年。结果:根据检索策略,检索到91项相关研究,其中4项纳入分析。亚利桑那性体验量表(ASEX)评分(平均差[MD]4.96,95%置信区间[CI]2.78-7.13,p p = 0.001)低于对照组。结论:白癜风患者发生性功能障碍的风险更大。此外,女性白癜风与性功能障碍之间的相关性比男性更强。关键信息白癜风患者发生性功能障碍的风险更大。女性白癜风与性功能障碍之间的相关性比男性更强。
期刊介绍:
Annals of Medicine is one of the world’s leading general medical review journals, boasting an impact factor of 5.435. It presents high-quality topical review articles, commissioned by the Editors and Editorial Committee, as well as original articles. The journal provides the current opinion on recent developments across the major medical specialties, with a particular focus on internal medicine. The peer-reviewed content of the journal keeps readers updated on the latest advances in the understanding of the pathogenesis of diseases, and in how molecular medicine and genetics can be applied in daily clinical practice.