Diagnostic pré-implantatoire

EMC - Gynécologie-Obstétrique Pub Date : 2004-05-01 DOI:10.1016/j.emcgo.2004.02.002

H Dechaud (Maître de conférences des Universités, praticien hospitalier) , T Anahory (Praticien hospitalier) , A Girardet (Docteur es Science) , C Coubes (Praticien hospitalier) , V Cacheux (Maître de conférences des Universités, praticien hospitalier) , S Hamamah (Professeur des Universités, praticien hospitalier) , M Claustres (Professeur des Universités, praticien hospitalier)

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引用次数: 3

Abstract

Fourteen years ago, the first preimplantation genetic diagnosis was described in the literature. The aim of the preimplantation genetic diagnosis is to analyse genes or chromosomes of embryos just before their transfer into the uterus. This technique avoids, for an identified pathology, the birth of children suffering from this pathology or repetitive medical abortions after prenatal diagnosis. The preimplantation genetic diagnosis needs to be performed by a multidisciplinary team working in well defined legal conditions. The preimplantation genetic diagnosis procedure includes an in vitro fertilization and intracytoplasmic sperm injection, a biopsy of one embryo cell and the genetic analysis of this cell. However, only a restricted number of genetic pathologies can benefit from such management. Preimplantation genetic diagnosis is a promising procedure for numerous patients. However, the evolution of its indications highlights the importance of informing both the couples and the society.

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着床前诊断

14年前，文献中首次描述了胚胎植入前遗传学诊断。胚胎植入前遗传学诊断的目的是在胚胎移植到子宫之前分析胚胎的基因或染色体。这种技术避免了对于已确定的病理，患有这种病理的儿童的出生或产前诊断后重复的药物流产。植入前遗传学诊断需要在明确的法律条件下由多学科团队进行。植入前遗传学诊断程序包括体外受精和卵胞浆内单精子注射，一个胚胎细胞活检和该细胞的遗传分析。然而，只有有限数量的遗传疾病可以从这种管理中受益。胚胎植入前遗传学诊断对许多患者来说是一种很有前途的方法。然而，其迹象的演变突出了告知夫妇和社会的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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EMC - Gynécologie-Obstétrique

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