{"title":"Tigecycline: a novel broad spectrum antibiotic","authors":"Dilip Nathwani","doi":"10.1002/fps.23","DOIUrl":null,"url":null,"abstract":"<p>Healthcare associated infections (HAIs) affect around 2 million people admitted to acute care hospitals in the USA.<sup>1</sup> Approximately 9 per cent of patients in UK hospitals suffer from an infection acquired during their hospital stay,<sup>2</sup> many of which are due to multi-resistant, Gram-positive and Gram-negative patho-gens. The incidence of colonisation and infection with these pathogens continues to rise due to failures in hospital hygiene, selective pressures created by overuse of antibiotics, and mobile elements that can enc-ode bacterial resistance mechanisms. Copyright © 2006 John Wiley & Sons, Ltd.</p>","PeriodicalId":100566,"journal":{"name":"Future Prescriber","volume":"7 1","pages":"29-33"},"PeriodicalIF":0.0000,"publicationDate":"2008-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/fps.23","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future Prescriber","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/fps.23","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Healthcare associated infections (HAIs) affect around 2 million people admitted to acute care hospitals in the USA.1 Approximately 9 per cent of patients in UK hospitals suffer from an infection acquired during their hospital stay,2 many of which are due to multi-resistant, Gram-positive and Gram-negative patho-gens. The incidence of colonisation and infection with these pathogens continues to rise due to failures in hospital hygiene, selective pressures created by overuse of antibiotics, and mobile elements that can enc-ode bacterial resistance mechanisms. Copyright © 2006 John Wiley & Sons, Ltd.
替加环素:一种新型广谱抗生素
保健相关感染(HAIs)影响着美国急症医院收治的约200万人1。英国医院约9%的患者在住院期间感染,2其中许多是由多重耐药、革兰氏阳性和革兰氏阴性病原体引起的。由于医院卫生条件不佳、过度使用抗生素造成的选择性压力以及可编码细菌耐药机制的移动元件,这些病原体的定植和感染发生率继续上升。版权所有©2006 John Wiley &儿子,有限公司
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