Combined solutions using biosurfactants based on water-insolute biologically active compounds

A. Prokopalo, I. Maziar, N. Zayarnyuk, A. Krychkovska, O. Karpenko, V. Lubenets
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Abstract

Solutions of biologically active substances insoluble in water (thiosulfoesters, anthraquinone derivatives, pyrazoline) were obtained using a combined solvent and biogenic surfactants. For this purpose were used rhamnolipids, their biocomplex with polysaccharides synthesized by the Pseudomonas SP strain. PS-17, trehalosolipids of the Rhodococcus erythropolis AU-1 strain, and the commercial biosurfactant surfactant. Aqueous dispersed systems of the studied substances were also obtained. The research results have prospects for use in pharmacy.
使用基于水溶质生物活性化合物的生物表面活性剂的组合溶液
采用复合溶剂和生物源表面活性剂制备了不溶于水的生物活性物质(硫代砜酯、蒽醌衍生物、吡唑啉)的溶液。为此,利用鼠李糖脂及其与假单胞菌SP菌株合成的多糖的生物复合物。PS-17,红红红球菌AU-1菌株的海藻脂质,以及商用生物表面活性剂。还得到了所研究物质的水分散体系。研究结果在药学领域具有广阔的应用前景。
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