Preparation and research of gelatine hydrogel anti-bedsore materials properties

Abstract

The formation of the hydrogel polymer matrix duringthe gelatin cross-linking with dioxirane derivatives of polyoxyethylene glycolswere studied.The optimal conditions for their synthesis were determined. The characteristics of the hydrogel (swelling in different media, mechanical properties at different temperatures) were obtained depending on the type of dioxirane derivative and prepolymer ratio. The possibility of introducing several drugs into hydrogels was established and the release of these drugs was found to be prolonged.