Influence of a high-frequency electromagnetic field at 2.45 GHz on cytokine productions in macrophage-like U937 cells

2012 IEEE MTT-S International Microwave Workshop Series on Innovative Wireless Power Transmission: Technologies, Systems, and Applications Pub Date : 2012-05-10 DOI:10.1109/IMWS.2012.6215788

E. Narita, T. Sakurai, Y. Suzuki, M. Taki, J. Miyakoshi

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Abstract

The relationship between exposure to electromagnetic fields (EMF) and health risks is of increasing interest. Although general concern regarding the potential hazards of exposure to an EMF has led to many epidemiological investigations, the effects of EMF exposure on human cells are still controversial. In vitro study, the cellular immune effects of EMF are discussed. We investigated the effects of a high-frequency electromagnetic field (HFEMF) at 2.45 GHz on cytokine (such as, human interleukin 1β (IL-1β), interleukin 6 (IL-6), interleukin 8 (IL-8), interleukin 10 (IL-10), and tumor necrosis factor-α (TNF-α)) productions in human monoblastic U937 cells. Our results showed that the exposure to a HFEMF of 2.45 GHz at SAR of 2 and 10 W/kg for 4 and 24 hours has no significant effect on IL-1β, IL-6, IL-8, IL-10 and TNF-α productions in U937 cells.

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2.45 GHz高频电磁场对巨噬细胞样U937细胞产生细胞因子的影响

电磁场暴露与健康风险之间的关系日益引起人们的关注。虽然对接触电磁场的潜在危害的普遍关注导致了许多流行病学调查，但接触电磁场对人体细胞的影响仍然存在争议。在体外研究中，讨论了电磁场的细胞免疫效应。我们研究了2.45 GHz高频电磁场(HFEMF)对人单核细胞U937细胞中细胞因子(如人白细胞介素1β (IL-1β)、白细胞介素6 (IL-6)、白细胞介素8 (IL-8)、白细胞介素10 (IL-10)和肿瘤坏死因子-α (TNF-α))产生的影响。结果表明，在2.45 GHz、2和10 W/kg的辐射强度下暴露4和24小时，对U937细胞IL-1β、IL-6、IL-8、IL-10和TNF-α的产生均无显著影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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2012 IEEE MTT-S International Microwave Workshop Series on Innovative Wireless Power Transmission: Technologies, Systems, and Applications

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