Feasibility Study of Multi-Wavelength Optical Probe to Analyze Magnesium Implant Degradation Effects

Hafiz Wajahat Hassan, Annakutty Mathew, H. Khan, O. Korostynska, P. Mirtaheri
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引用次数: 4

Abstract

Near-infrared spectroscopy (NIRS) is a rapidly developing and promising technology with potential for spectro-graphic analysis. Understanding NIRS measurements on the implant-tissue interface for hydrogen gas formation as part of degradation is essential for interpreting the biodegradable Magnesium (Mg) based implants. This paper introduces novel NIR optical probe that can assess the state of Mg implant's degradation when in contact with biological tissues. A tissue-mimicking phantom (TMP) to mimic biological tissue's optical properties helps investigate changes in reflectance spectra due to bubble formation at the implant-tissue interface. Spectra taken from different TMP samples containing biodegradable Mg and non-degradable Titanium (Ti) disk are suitable for evaluating the implant's interaction. The results show that the reflection in TMP for samples containing Mg disks, confirms the presence of hydrogen bubbles at the surface of implants. Multi-distance optical probe with depth selectivity of 3mm and 4mm has shown to be an effective tool to monitor bubble effect on different samples.
多波长光学探针分析镁植入物降解效果的可行性研究
近红外光谱(NIRS)是一项发展迅速、前景广阔的光谱分析技术。了解近红外光谱测量的植入物-组织界面的氢气形成作为降解的一部分是解释可生物降解镁(Mg)基植入物的必要条件。本文介绍了一种新型的近红外光学探针,它可以评估镁植入物与生物组织接触时的降解状态。组织模拟模体(TMP)模拟生物组织的光学特性,有助于研究由于在植入物-组织界面形成气泡而导致的反射光谱变化。从含有可生物降解Mg和不可降解钛(Ti)盘的不同TMP样品中提取的光谱适合于评估植入物的相互作用。结果表明,在含有Mg片的样品中,TMP的反射证实了植入物表面存在氢气泡。具有3mm和4mm深度选择性的多距离光学探针已被证明是监测不同样品上气泡效应的有效工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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