Prognostic Significance of Regional Arterial Stiffness for Stroke in Hypertension.

IF 0.6 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Kardiologie Pub Date : 2015-09-01 Epub Date: 2015-05-28 DOI:10.1159/000381795

Takuro Kubozono, Mitsuru Ohishi

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Abstract

Background: Hypertension is strongly associated with cardiovascular disease. It has been reported that arterial stiffness is related to cardiovascular mortality and morbidity in hypertensive patients and that the physiological evaluation of arterial stiffness may assist clinicians in the early detection of atherosclerosis.

Summary: It has been demonstrated that increased arterial stiffness is an independent predictor of cardiovascular disease, including stroke. Arterial stiffness is associated with structural changes in the brain. However, the stiffness responses of muscular arteries are different from those of elastic arteries, and so the impact of arterial stiffness and the conclusions to be drawn may be different depending on the region in which the measurement is taken.

Key messages: In this review, we summarize the current literature describing the association between arterial stiffness, including carotid-femoral and brachial-ankle pulse wave velocity and cardio-ankle vascular index, and cardiovascular disease, specifically stroke. We discuss the utility and prognostic significance of regional arterial stiffness measurements.

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区域动脉僵硬度对高血压脑卒中的预后意义

背景：高血压与心血管疾病密切相关：高血压与心血管疾病密切相关。据报道，动脉僵硬度与高血压患者的心血管死亡率和发病率有关，对动脉僵硬度进行生理评估有助于临床医生早期发现动脉粥样硬化。动脉僵化与大脑结构变化有关。然而，肌肉动脉的僵化反应不同于弹性动脉，因此动脉僵化的影响和得出的结论可能因测量区域的不同而不同：在这篇综述中，我们总结了目前描述动脉僵化（包括颈动脉-股动脉和肱动脉-踝动脉脉搏波速度和贲门-踝动脉血管指数）与心血管疾病（尤其是中风）之间关系的文献。我们讨论了区域动脉僵化测量的效用和预后意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Kardiologie

CiteScore

1.20

自引率

11.10%

发文量