Treatment of Metastatic Colorectal Cancer in a Pregnant Woman with Lynch Syndrome- A Case Report

Abstract

Colorectal carcinoma is the third most common cancer diagnosed in females in the United States [1]. It accounts for 8% of the new cancers diagnosed in women and an estimated 63,700 new cases of CRC expected in 2015. CRC diagnosed in pregnancy is not common with an incidence of 1 in 13,000 pregnancies [2-4]. Management of a pregnant woman with CRC is challenging due to various unknowns to guide the antineoplastic treatment decision. CRC cases during pregnancy and use of chemotherapy agents have reported in the past decade [5-12]. Reporting of management of such situations is helpful in assisting clinicians to further investigating the use of chemotherapy agents in pregnancy. We report an unusual, but the challenging case of 24-year-old pregnant women diagnosed with metastatic colon cancer as a consequence of lunch syndrome treated with FOLFOX chemo regimen with no apparent fetal harm.