AZO-POLÍMERO MOLECULARMENTE IMPRESSO COMO ESTRATÉGIA NO DESENVOLVIMENTO DE UMA NOVA PLATAFORMA SENSORIAL PARA DETECÇÃO DE ÁCIDO ÚRICO

Abstract

This present work was studied the development of a molecularly imprinted polymer (MIP) based on the poly(azo-Bismarck Y) for detection of uric acid. The film MIP was electrodeposited on the fluorine-doped tin-oxide (FTO) glass electrode surface by electropolymerization of Bismarck Brown Y monomer in presence of uric acid as the template molecule. The MIP-poly(azo-Bismarck Y) sensor displays a good electrochemical response, high sensitivity and selectivity in specific binding of the uric acid. Under the optimized experimental conditions, the voltammetric response of the proposed sensor was linear in the concentration range of 0.20 mmol L to 0.60 mmol L, with detection limit of 0.17 mmol L.