Inhibitory Capacity of Clay Mask 96% Ethanol Extract from Bitter Melon (Momordica charantia L.) Against Staphylococcus aureus

JURNAL SAINS NATURAL Pub Date : 2022-07-30 DOI:10.31938/jsn.v12i3.413

Siti Qur'aniati, I. Widhyastini, D. Susanty

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Abstract

Momordica charantia L. commonly known as bitter melon plant, is widely used as a treatment for various diseases, including skin infections. The purpose of this study was to determine the highest concentration of bitter melon extract and infusion in inhibiting the growth of Staphylococcus aureus bacteria. This research was conducted using the disc diffusion method and evaluation of the quality of the clay mask was carried out on the growth of Staphylococcus aureus bacteria. The results showed that 96 % ethanol extract of bitter melon at a concentration of 100% had an inhibitory effectiveness of 6.32 mm and was higher than that of 4.85 mm of bitter melon infusion. The clay mask formula of 96% ethanol extract of bitter melon with concentrations of 5 % (F1), 7.5 % (F2) and 10 % (F3) gave a fairly good evaluation of physical quality with an inhibition zone of 5.0 mm; 7.06 mm and 7.30 mm, respectively. The clay mask of 96% ethanol extract of bitter melon fruit F1, F2 and F3 belongs to the medium category in inhibiting bacteria.keywords: inhibition; ethanol extract; clay mask; Momordica charantia L.; Staphylococcus aureusABSTRAKDaya Hambat Masker Clay Ekstrak Etanol 96% Buah Pare (Momordica charantia L.) terhadap Bakteri Staphylococcus aureusMomordica charantia L. umumnya dikenal dengan tanaman pare, digunakan sebagai pengobatan terhadap berbagai penyakit, diantaranya infeksi pada kulit. Penelitian ini bertujuan untuk mengetahui konsentrasi tertinggi ekstrak dan infusa buah pare dalam menghambat pertumbuhan bakteri Staphylococcus aureus. Penelitian ini dilakukan menggunakan metode difusi cakram dan evaluasi mutu masker clay dilakukan terhadap pertumbuhan bakteri Staphylococcus aureus. Hasil penelitian menunjukkan bahwa ekstrak etanol 96 % buah pare pada konsentrasi 100 % memiliki efektivitas daya hambat sebesar 6,32 mm dan lebih tinggi dibandingkan dengan infusa buah pare 4,85 mm. Formula masker clay ekstrak etanol 96 % buah pare konsentrasi 5 % (F1) ; 7,5 % ; (F2) dan 10 % (F3) memberikan hasil evaluasi mutu fisik yang cukup baik dengan zona hambat berturut-turut 5,0 mm ; 7,06 mm dan 7,30 mm. Masker clay ekstrak etanol 96% buah pare F1, F2 dan F3 termasuk ke dalam kategori sedang dalam menghambat bakteri.Kata kunci: daya hambat; ekstrak etanol; masker clay; Momordica charantia L.; Staphylococcus aureus

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苦瓜泥膜96%乙醇提取物的抑菌性能研究对抗金黄色葡萄球菌

苦瓜(Momordica charantia L.)俗称苦瓜植物，被广泛用于治疗各种疾病，包括皮肤感染。本研究的目的是确定苦瓜提取物和浸液的最高浓度对金黄色葡萄球菌生长的抑制作用。本研究采用圆盘扩散法，对金黄色葡萄球菌的生长进行了粘土掩膜质量评价。结果表明，96%乙醇提取物浓度为100%时，其抑菌效果为6.32 mm，高于4.85 mm的苦瓜浸液。以苦瓜96%乙醇提取物(5% (F1)、7.5% (F2)和10% (F3)为浓度)的粘土掩膜配方，其物理品质评价较好，抑制带为5.0 mm;7.06毫米和7.30毫米。苦瓜果实F1、F2和F3 96%乙醇提取物的粘土面膜在抑菌作用上属于中等范畴。关键词:抑制;乙醇提取物;粘土面具;苦瓜;金黄色葡萄球菌(Momordica charantia L.) terhadap Bakteri金黄色葡萄球菌Momordica charantia L. umumnya dikenal dengan tanaman Pare, digunakan sebagai pengobatan terhadap berbagai penyakit, diantaranya infeksi paada kulit。Penelitian ini bertujuan untuk mengetahui konsentrasi tertingi ekstrak dan infusbuah parparam menghambat pertumbuhan bakteri金黄色葡萄球菌。潘利特尼·迪拉坎·蒙古纳坎方法:对迪拉坎·蒙古纳坎进行扩散和评价。Hasil penelitian menunjukkan bahwa ekstrak etan96 % buah parada konsentrasi 100% memiliki efektivitas daya hambat sebesar 6,32 mm，但lebih tinggi dibandingkan dengan infacha parah 4,85 mm。配方掩蔽剂粘土乙醇96%，苯酚5% (F1);7、5%;(F2)丹10% (F3)成员间的土壤质量评价:土豆泥、土豆泥、土豆泥、土豆泥、土豆泥、土豆泥、土豆泥5 0 mm;7、06毫米丹7、30毫米。蒙面粘土ekstrak乙醇96% buah pare F1, F2和F3 termasuk ke dalam kategori sedang dalam menghambat bakteri。Kata kunci;ekstrak etanol;戴面具的人粘土;苦瓜;金黄色葡萄球菌

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