Analysis of Delta (Indian) Variant of SARS-CoV-2 Infectivity using Resonant Recognition Model

Abstract

This manuscript is continuation of our previous work, where we have analyzed different variants of SARS-CoV-2 virus (UK, South African, Brazilian, and Indian (Kappa)) using Resonant Recognition Model (RRM), which is biophysical model capable to analyze protein function and interaction. We have previously identified correlation between infectivity of these SARS-CoV-2 virus variants with strength of signal at RRM characteristic frequencies for each variant. Here, we have extended this analysis for Delta (Indian) SARS-CoV-2 virus variant, which is extremely infectious and is rapidly spreading around the World. Our results with Delta (Indian) variant are in complete agreement with our previous RRM proposition that viral infectivity is proportional to strength of signal at RRM characteristic frequency. These results can explain why Delta (Indian) variant is more infectious. With strong correlation obtained in all these examples, we can propose here that RRM model can be used as general tool to analyze infectivity of mutated virus variants.