TL 18131 - Functional evaluation of hyaluronic acid infiltration in the subtalar joint of patients with posttraumatic osteoarthritis

Fernanda Ferreira Gomes, Henrique Mansur, Maria Laura Silva Gomes, D. Ramalho, Isnar Moreira de Castro Júnior
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Abstract

Objective: To assess the efficacy of intra-articular viscosupplementation in patients with symptomatic subtalar osteoarthritis after calcaneal fracture. Methods: Thirty-eight patients with a mean age of 50 years were divided into 3 groups: hyaluronic acid (HA) alone, corticoids alone or hyaluronic acid and corticoids combined. Three consecutive doses of the appropriate medication were administered at one-week intervals. The patients were evaluated for pain and hindfoot function using the American Orthopedic Foot and Ankle Society (AOFAS) scale and the visual analog scale (VAS) at 4 different timepoints (before infiltration and 4, 12 and 24 weeks after infiltration). Results: There was significant improvement in the AOFAS score (from medians of 55 and 73 at baseline to 99 and 100 after 24 weeks; p<0.001) and the VAS score (from medians of 8 and 7 before infiltration to 1 and 2 at 24 weeks after infiltration; p<0.001) scores in the groups with hyaluronic acid alone and in combination with corticoid, respectively. In group 2, the scores improved after only 4 weeks (from 83 to 91.5 and from 7 to 5), returning to near-baseline values at the end of the follow-up (from 83 to 82.5 and from 7 to 7). Conclusion: Infiltration with hyaluronic acid was effective and safe and should be included in the therapeutic arsenal of conservative treatments for symptomatic posttraumatic subtalar osteoarthritis.
tl18131 -创伤后骨关节炎患者距下关节透明质酸浸润的功能评价
目的:评价关节内补充粘剂治疗跟骨骨折后症状性距下骨关节炎的疗效。方法:38例平均年龄50岁的患者分为单独使用透明质酸组、单独使用皮质激素组和透明质酸与皮质激素联合使用组。每隔一周给药三次。采用美国骨科足踝学会(AOFAS)评分和视觉模拟评分(VAS)在4个不同时间点(浸润前、浸润后4周、12周和24周)评估患者的疼痛和后足功能。结果:AOFAS评分有显著改善(从基线时的中位数55和73提高到24周后的99和100;p<0.001)和VAS评分(从浸润前的中位数8和7到浸润后24周的中位数1和2;P <0.001),分别与单独使用透明质酸组和与皮质激素联合使用组比较。在第2组,仅在4周后评分就有所提高(从83到91.5和从7到5),在随访结束时恢复到接近基线值(从83到82.5和从7到7)。结论:透明质酸浸润是有效和安全的,应纳入有症状的创伤后距下骨关节炎的保守治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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