Bacteriological pattern of urinary tract infection in men with symptomatic benign prostatic hyperplasia at a tertiary hospital in Nigeria

IF 2.5 3区 工程技术 Q2 BIOLOGY
P. Ngwu, IE Ihedoro, EI Kalu
{"title":"Bacteriological pattern of urinary tract infection in men with symptomatic benign prostatic hyperplasia at a tertiary hospital in Nigeria","authors":"P. Ngwu, IE Ihedoro, EI Kalu","doi":"10.17352/jbm.000032","DOIUrl":null,"url":null,"abstract":"Introduction/Background: Benign Prostatic Hyperplasia (BPH) is characterized by narrowing of the prostatic urethra with resultant difficulty in passing urine, stasis, and a predisposition to urinary tract infection. The objective of this study is to identify the prevalence of urinary tract infections, common organisms isolated, their antimicrobial sensitivity pattern, and the relationship of co-morbidities with urinary tract infection in this population. Materials and methods: All patients who presented to our urology team with bladder outlet obstruction secondary to benign prostatic hyperplasia between January 2020 and January 2021 were included. Information on age, occupation, co-morbid conditions, urine microscopy, culture, and sensitivity patterns were obtained and analyzed using SPSS version 25. Midstream urine samples were collected from 172 BPH patients. Microscopy, culture, and antibiotic susceptibility tests were carried out. Results: From our study, the prevalence of bacteriuria was 67.9% with the 65-74 and 45-54 age groups having the highest and the least prevalence of bacteriuria (88.9% and 33.3% respectively). The most common organisms cultured from their urine were Pseudomonas (17.9%), E. coli (14.3%), Coliforms (10.7%), and Klebsiella (10.7%). Sensitivity patterns of these microorganisms revealed the highest sensitivity to the fluoroquinolones (25.9%) followed by Nitrofurantoin (14.8%) and Ceftriaxone and Cefoxitin (7.4%). The least sensitivity was to Augmentin and Gentamycin. Conclusion: Bacteriuria is common in patients with BPH. Pseudomonas spp was the commonest isolated organism in our study and most isolated organisms were susceptible to the fluoroquinolones.","PeriodicalId":48617,"journal":{"name":"Yale Journal of Biology and Medicine","volume":null,"pages":null},"PeriodicalIF":2.5000,"publicationDate":"2022-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Yale Journal of Biology and Medicine","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.17352/jbm.000032","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Introduction/Background: Benign Prostatic Hyperplasia (BPH) is characterized by narrowing of the prostatic urethra with resultant difficulty in passing urine, stasis, and a predisposition to urinary tract infection. The objective of this study is to identify the prevalence of urinary tract infections, common organisms isolated, their antimicrobial sensitivity pattern, and the relationship of co-morbidities with urinary tract infection in this population. Materials and methods: All patients who presented to our urology team with bladder outlet obstruction secondary to benign prostatic hyperplasia between January 2020 and January 2021 were included. Information on age, occupation, co-morbid conditions, urine microscopy, culture, and sensitivity patterns were obtained and analyzed using SPSS version 25. Midstream urine samples were collected from 172 BPH patients. Microscopy, culture, and antibiotic susceptibility tests were carried out. Results: From our study, the prevalence of bacteriuria was 67.9% with the 65-74 and 45-54 age groups having the highest and the least prevalence of bacteriuria (88.9% and 33.3% respectively). The most common organisms cultured from their urine were Pseudomonas (17.9%), E. coli (14.3%), Coliforms (10.7%), and Klebsiella (10.7%). Sensitivity patterns of these microorganisms revealed the highest sensitivity to the fluoroquinolones (25.9%) followed by Nitrofurantoin (14.8%) and Ceftriaxone and Cefoxitin (7.4%). The least sensitivity was to Augmentin and Gentamycin. Conclusion: Bacteriuria is common in patients with BPH. Pseudomonas spp was the commonest isolated organism in our study and most isolated organisms were susceptible to the fluoroquinolones.
尼日利亚一家三级医院男性症状性良性前列腺增生患者尿路感染的细菌学模式
简介/背景:良性前列腺增生(BPH)的特点是前列腺尿道变窄,导致排尿困难、瘀血和易发生尿路感染。本研究的目的是确定尿路感染的患病率,分离的常见微生物,它们的抗菌药物敏感性模式,以及合并症与尿路感染的关系。材料和方法:纳入2020年1月至2021年1月期间所有以良性前列腺增生继发膀胱出口梗阻就诊的泌尿科团队患者。年龄、职业、合并症、尿液显微镜、培养和敏感性模式的信息获得并使用SPSS版本25进行分析。收集172例BPH患者的中游尿液样本。进行显微镜、培养和抗生素敏感性试验。结果:本组细菌尿率为67.9%,其中65 ~ 74岁和45 ~ 54岁细菌尿率最高和最低,分别为88.9%和33.3%。从他们的尿液中培养的最常见的微生物是假单胞菌(17.9%)、大肠杆菌(14.3%)、大肠菌群(10.7%)和克雷伯氏菌(10.7%)。这些微生物对氟喹诺酮类药物的敏感性最高(25.9%),其次是呋喃妥英(14.8%)和头孢曲松和头孢西丁(7.4%)。对Augmentin和庆大霉素的敏感性最低。结论:细菌性尿路在前列腺增生患者中较为常见。假单胞菌是本研究中最常见的分离菌,大多数分离菌对氟喹诺酮类药物敏感。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Yale Journal of Biology and Medicine
Yale Journal of Biology and Medicine Biochemistry, Genetics and Molecular Biology-General Biochemistry,Genetics and Molecular Biology
CiteScore
5.00
自引率
0.00%
发文量
41
期刊介绍: The Yale Journal of Biology and Medicine (YJBM) is a graduate and medical student-run, peer-reviewed, open-access journal dedicated to the publication of original research articles, scientific reviews, articles on medical history, personal perspectives on medicine, policy analyses, case reports, and symposia related to biomedical matters. YJBM is published quarterly and aims to publish articles of interest to both physicians and scientists. YJBM is and has been an internationally distributed journal with a long history of landmark articles. Our contributors feature a notable list of philosophers, statesmen, scientists, and physicians, including Ernst Cassirer, Harvey Cushing, Rene Dubos, Edward Kennedy, Donald Seldin, and Jack Strominger. Our Editorial Board consists of students and faculty members from Yale School of Medicine and Yale University Graduate School of Arts & Sciences. All manuscripts submitted to YJBM are first evaluated on the basis of scientific quality, originality, appropriateness, contribution to the field, and style. Suitable manuscripts are then subject to rigorous, fair, and rapid peer review.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信