Regional Differences in Incident Prefrailty and Frailty

Journal of Womens Health Care Pub Date : 2017-09-01 DOI:10.1089/JWH.2016.6041

S. Tom, A. Wyman, N. Woods, F. Anderson, J. Adachi, R. Chapurlat, J. Compston, C. Cooper, A. Díez-Pérez, A. Díez-Pérez, S. Gehlbach, S. Greenspan, F. Hooven, L. March, J. Netelenbos, J. Nieves, J. Pfeilschifter, M. Rossini, C. Roux, K. Saag, E. Siris, S. Silverman, N. Watts, A. LaCroix

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引用次数: 2

Abstract

Abstract Background and Objectives: The extent to which greater frailty among American compared with European women reflects individual-level characteristics has not been well studied. To test the hypothesis that cardiometabolic conditions and depression and anxiety confound the relationship between region and incident prefrailty and frailty in American compared with European women. Materials and Methods: The Global Longitudinal Study of Osteoporosis in Women (GLOW) is a 5-year observational cohort study of women aged ≥55 years. A total of 19,674 participants from the United States and Europe were nonfrail at baseline and provided information on characteristics, including body mass index, depression and anxiety, and cardiovascular disease. We used multivariable Cox proportional hazards models to examine the relationship between region and incident frailty and prefrailty. Results: Over 40% of respondents became prefrail or frail during follow-up. Adjusting for age, body mass index, depression and anxiety, ...

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事件脆弱性和脆弱性的地区差异

背景与目的:与欧洲女性相比，美国女性更脆弱在多大程度上反映了个体层面的特征，这一点尚未得到很好的研究。为了验证一种假设，即心脏代谢状况、抑郁和焦虑混淆了美国女性与欧洲女性的地区和事件易感性和脆弱性之间的关系。材料和方法:全球女性骨质疏松症纵向研究(GLOW)是一项针对年龄≥55岁女性的5年观察性队列研究。来自美国和欧洲的19674名参与者在基线时身体不虚弱，并提供了有关特征的信息，包括体重指数、抑郁和焦虑以及心血管疾病。我们使用多变量Cox比例风险模型来检验地区与事件脆弱性和脆弱性之间的关系。结果:超过40%的受访者在随访期间变得虚弱或虚弱。根据年龄、体重指数、抑郁和焦虑等因素进行调整……

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Journal of Womens Health Care

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