Curiosity and mesolimbic functional connectivity drive information seeking in real life.

IF 3.9 2区医学 Q2 NEUROSCIENCES

Social cognitive and affective neuroscience Pub Date : 2023-02-23 DOI:10.1093/scan/nsac050

Kathrin C J Eschmann, Duarte F M M Pereira, Ashvanti Valji, Vera Dehmelt, Matthias J Gruber

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引用次数: 0

Abstract

Curiosity reflects an individual's intrinsic motivation to seek information in order to close information gaps. In laboratory-based experiments, both curiosity and information seeking have been associated with enhanced neural dynamics in the mesolimbic dopaminergic circuit. However, it is unclear whether curiosity and dopaminergic dynamics drive information seeking in real life. We investigated (i) whether curiosity predicts different characteristics of real-life information seeking and (ii) whether functional connectivity within the mesolimbic dopaminergic circuit is associated with information seeking outside the laboratory. Up to 15 months before the COVID-19 pandemic, curiosity and anxiety questionnaires and a 10-minute resting-state functional magnetic resonance imaging session were conducted. In a follow-up survey early during the COVID-19 pandemic, participants repeated the questionnaires and completed an additional questionnaire about their COVID-19-related information seeking. Individual differences in curiosity but not anxiety were positively associated with the frequency of information-seeking behaviour. Additionally, the frequency of information seeking was predicted by individual differences in resting-state functional connectivity between the ventral tegmental area and the nucleus accumbens. The present translational study paves the way for future studies on the role of curiosity in real-life information seeking by showing that both curiosity and the mesolimbic dopaminergic functional network support real-life information-seeking behaviour.

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好奇心和中边缘功能连接驱动了现实生活中的信息寻求。

好奇心反映了个人寻求信息以缩小信息差距的内在动机。在实验室实验中，好奇心和信息寻求都与中边缘多巴胺能回路的神经动力学增强有关。然而，目前尚不清楚好奇心和多巴胺能动力学是否驱动了现实生活中的信息寻求。我们研究了（i）好奇心是否预测现实生活中信息寻求的不同特征，以及（ii）中边缘多巴胺能回路内的功能连接是否与实验室外的信息寻求有关。最多15 新冠肺炎大流行前几个月，进行了好奇心和焦虑问卷调查，并进行了10分钟的静息状态功能性磁共振成像。在新冠肺炎大流行早期的一项后续调查中，参与者重复了问卷调查，并完成了一份关于新冠肺炎相关信息寻求的额外问卷调查。好奇心而非焦虑的个体差异与信息寻求行为的频率呈正相关。此外，信息寻求的频率是通过腹侧被盖区和伏隔核之间静息状态功能连接的个体差异来预测的。本转化研究表明，好奇心和中边缘多巴胺能功能网络都支持现实生活中的信息寻求行为，为未来研究好奇心在现实生活中信息寻求中的作用铺平了道路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Social cognitive and affective neuroscience 医学-神经科学

CiteScore

6.80

自引率

4.80%

发文量

审稿时长

4-8 weeks

期刊介绍： SCAN will consider research that uses neuroimaging (fMRI, MRI, PET, EEG, MEG), neuropsychological patient studies, animal lesion studies, single-cell recording, pharmacological perturbation, and transcranial magnetic stimulation. SCAN will also consider submissions that examine the mediational role of neural processes in linking social phenomena to physiological, neuroendocrine, immunological, developmental, and genetic processes. Additionally, SCAN will publish papers that address issues of mental and physical health as they relate to social and affective processes (e.g., autism, anxiety disorders, depression, stress, effects of child rearing) as long as cognitive neuroscience methods are used.