Outcome variables of right anterolateral mini-thoracotomy versus complete sternotomy in atrial septal defect closure: A randomized controlled trial

Saleh Raslan , Mohammed Sharaa , Medhat Refaie , Warda Demerdash Khalifa Ali , Abdelsalam M. Elhenawy
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引用次数: 2

Abstract

Background

Over the last decades, atrial septal defect repair (ASD) as one of the most congenital anomalies has been customarily repaired via sternotomy incision. This technique is associated with very low operative risks and excellent outcomes but with poor esthetic results for the patients. Consequently, right anterolateral mini thoracotomy was invented as a substitute technique aiming for superior cosmetic results. Our study aim was to compare the perioperative outcomes for different approaches.

Methods

Forty patients (15 males, 25 females) with ASDs were randomly assigned to have either one of these two approaches at our institution from March 2013 until May 2016. The patients' ages ranged from 2 to 53 years old. Based on their randomization, group I (20 patients), had right anterolateral mini-thoracotomy (RALT) and group II (20 patients) who had sternotomy for surgical closure of ASD. We collected the different demographic, baseline, perioperative and postoperative characteristics.

Results

The patients in both groups were similar in age preoperative comorbidities and ejection fraction but more females were in RALT group. There was a highly statistically significant prolonged pump-run time in the thoracotomy group than the sternotomy group with p-value = 0.004. Interestingly, in the thoracotomy group, mechanical ventilation time (hours) was shorter with p-value = 0.002. There were similar blood transfusion rate, chest tube drainage, intensive care unit stay and hospital length of stay. However, more wound infection was found in the sternotomy group which was statistically significant (p-value = 0.035). There were no patients requiring conversion to full sternotomy, no residual defect across the atrial septum and all patients were alive on a month follow-up of the hospital discharge.

Conclusions

Right anterolateral mini-thoracotomy is safe, cosmetic, effective and technically feasible and not inferior to the formal median sternotomy to repair ASDs surgically.

右前外侧小胸切开术与完全胸骨切开术治疗房间隔缺损的结局变量:一项随机对照试验
背景在过去的几十年里,房间隔缺损修复(ASD)作为最常见的先天性畸形之一,通常通过胸骨切开切口进行修复。该技术手术风险低,预后良好,但对患者的美观效果较差。因此,发明了右前外侧小开胸术作为替代技术,旨在获得更好的美容效果。我们的研究目的是比较不同入路的围手术期结果。方法选取2013年3月至2016年5月在我院收治的40例asd患者(男15例,女25例),随机分为两组。患者年龄2 ~ 53岁。根据随机分组,I组(20例)采用右前外侧小胸切开术(RALT), II组(20例)采用胸骨切开术手术封闭ASD。我们收集了不同的人口统计学、基线、围手术期和术后特征。结果两组患者年龄、术前合并症及射血分数相近,但RALT组女性患者较多。开胸组泵血运行时间较开胸组延长,p值= 0.004,具有高度统计学意义。有趣的是,开胸组机械通气时间(小时)更短,p值= 0.002。两组患者输血率、胸管引流、重症监护病房住院时间、住院时间相似。而胸骨切开组伤口感染发生率较高,差异有统计学意义(p值= 0.035)。没有患者需要转换为全胸骨切开术,房间隔没有残留缺损,所有患者在出院后一个月的随访中都存活。结论右前外侧小开胸术是一种安全、美观、有效、技术可行的术式,不逊色于胸骨正中切开术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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