Evaluation of some trace elements levels in sera of patients with Angina Pectoris in Erbil city

P. Ismail, A. Yousif, N. A. Ismail
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Abstract

Background: Angina pectoris(AP) is one of the most prevalent diseases in developed countries and is becoming an area of increasing concern in other parts of the world. Among the several causes of the disease alteration in the levels of trace elements are also important. Objectives : This study was undertaken in order to investigate the serum trace elements level in patients with Angina pectoris compared to healthy individuals, and to find whether there is any relationship between serum trace elements levels and patients with Angina pectoris.. Methods: The study involved 50 patients with Angina pectoris(AP) for evaluation of these trace elements level ( Se Cu, Zn ,Fe& Cr ) as well as TG, TC and LDL-C and HDL as compared with 50 control subjects . Results The results indicate that patients exhibited significant decrease in the serum of selinum(Se),zinc(Zn), copper(Cu), chromium(Cr) and iron(Fe) level (p<0.001) as compared to the healthy controls. TG, TC and LDL-C were elevated in patients and HDL-C was lower in our patients, Conclusions. Deficiency or suboptimal levels of micronutriants( Se ,Cu, Zn ,Fe& Cr ) may play a role in the development of Angina pectoris(AP). Measurement of serum trace elements level l might provide additional and useful laboratory test for the assessment of the patients with Angina pectoris and oral trace elements may have a role in therapy.
埃尔比勒市心绞痛患者血清中微量元素含量测定
背景:心绞痛(Angina pectoris, AP)是发达国家最常见的疾病之一,在世界其他地区日益受到关注。在引起该病的几个原因中,微量元素水平的改变也很重要。目的:研究心绞痛患者血清微量元素水平与健康人的比较,探讨血清微量元素水平与心绞痛患者之间是否存在关系。方法:对50例心绞痛患者(AP)进行微量元素(Se、Cu、Zn、fe、Cr)、TG、TC、LDL-C、HDL水平的测定,并与50例对照组进行比较。结果患者血清中硒(Se)、锌(Zn)、铜(Cu)、铬(Cr)、铁(Fe)含量较健康对照组显著降低(p<0.001)。患者TG、TC、LDL-C升高,HDL-C降低。微量营养素(硒、铜、锌、铁和铬)的缺乏或亚理想水平可能在心绞痛(AP)的发展中发挥作用。血清微量元素水平的测定可为心绞痛患者的诊断提供补充和有用的实验室检查,口服微量元素可能在治疗中起作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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