Effect of Temperature on DNA/RNA-Cadmium Oxide (CdO) Complex Nanoparticles Produced by Synchrotronic Laser Ablation Method in the Cancer Cells

Abstract

In this work, the effect of temperature of the ablation environment on the properties of Cadmium Oxide (CdO) nanoparticles produced by synchrotronic laser ablation method is investigated. To produce nanoparticles, Nd:YAG synchrotronic laser pulse with 1121 (nm) wavelength is used to emit Cadmium in the cancer cells. All test parameters were kept constant and cancer cells temperature was changed to produce samples at 20 and 65 °C. Then, ATR-FTIR, XRD, TEM and UV-Visible spectroscopy analyses were performed to investigate their properties. The results show that the size of nanoparticles is increased by increase in temperature of ablation environment. On the other hand, in the current experimental research, DNA/RNA-Cadmium Oxide (CdO) complex is created at the size of Nano. In this regard, same volume of DNA/RNA and Cadmium Oxide (CdO) solutions were mixed together and emitted by the second harmonic synchrotronic laser pulse of Nd:YAG with wavelength of 777 (nm). The DNA/RNA and Cadmium Oxide (CdO) solutions have been produced, separately, using synchrotronic laser ablation process. To produce them, synchrotronic laser pulse of Nd:YAG with wavelength of 1121 (nm) and pulse width of 7 (ns) and repeating frequency of 5 (Hz) was used. The results show that synchrotronic laser emission with wavelength of 777 (nm) is an appropriate method for producing DNA/RNA compounds in the size of Nano.