A Pilot Study of Application of the Stroke Riskometer Mobile App for Assessment of the Course and Clinical Outcomes of COVID-19 among Hospitalized Patients.

IF 2 Q3 PERIPHERAL VASCULAR DISEASE

Cerebrovascular Diseases Extra Pub Date : 2023-01-01 Epub Date: 2023-01-26 DOI:10.1159/000529277

Alexander Merkin, Sofya Akinfieva, Oleg N Medvedev, Rita Krishnamurthi, Alexey Gutsaluk, Ulf-Dietrich Reips, Rufat Kuliev, Evgeny Dinov, Igor Nikiforov, Nikolay Shamalov, Polina Shafran, Lyudmila Popova, Dmitry Burenchev, Valery Feigin

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引用次数: 0

Abstract

Introduction: Early determination of COVID-19 severity and health outcomes could facilitate better treatment of patients. Different methods and tools have been developed for predicting outcomes of COVID-19, but they are difficult to use in routine clinical practice.

Methods: We conducted a prospective cohort study of inpatients aged 20-92 years, diagnosed with COVID-19 to determine whether their individual 5-year absolute risk of stroke at the time of hospital admission predicts the course of COVID-19 severity and mortality. The risk of stroke was determined by the Stroke Riskometer mobile application.

Results: We examined 385 patients hospitalized with COVID-19 (median age 61 years). The participants were categorized based on COVID-19 severity: 271 (70.4%) to the "not severe" and 114 (29.6%) to the "severe" groups. The median risk of stroke the next day after hospitalization was significantly higher among patients in the severe group (2.83, 95% CI: 2.35-4.68) versus the not severe group (1.11, 95% CI: 1.00-1.29). The median risk of stroke and median systolic blood pressure (SBP) were significantly higher among non-survivors (12.04, 95% CI: 2.73-21.19) and (150, 95% CI: 140-170) versus survivors (1.31, 95% CI: 1.14-1.52) and (134, 95% CI: 130-135), respectively. Those who spent more than 2.5 h a week on physical activity were 3.1 times more likely to survive from COVID-19. Those who consumed more than one standard alcohol drink a day, or suffered with atrial fibrillation, or had poor memory were 2.5, 2.3, and 2.6 times more likely not to survive from COVID-19, respectively.

Conclusions: High risk of stroke, physical inactivity, alcohol intake, high SBP, and atrial fibrillation are associated with severity and mortality of COVID-19. Our findings suggest that the Stroke Riskometer app could be used as a simple predictive tool of COVID-19 severity and mortality.

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应用 "中风风险计 "手机应用评估住院病人 COVID-19 病程和临床结果的试点研究。

背景：早期确定 COVID-19 的严重程度和健康结果有助于更好地治疗患者。目前已开发出不同的方法和工具来预测 COVID-19 的预后，但这些方法和工具很难在常规临床实践中使用：我们对 20-92 岁确诊为 COVID-19 的住院患者进行了一项前瞻性队列研究，以确定他们入院时的 5 年中风绝对风险是否能预测 COVID-19 的严重程度和死亡率。中风风险由中风风险计移动应用程序确定：我们对 385 名 COVID-19 住院患者（中位年龄 61 岁）进行了检查。根据 COVID-19 的严重程度对参与者进行了分类：271 人（70.4%）属于 "不严重 "组，114 人（29.6%）属于 "严重 "组。严重组（2.83 [95% CI 2.35-4.68]）与非严重组（1.11 [95% CI 1.00-1.29]）相比，住院后第二天发生中风的中位风险明显更高。非幸存者（12.04 [95% CI 2.73-21.19]）和（150 [95% CI 140-170]）与幸存者（1.31 [95% CI 1.14-1.52]）、134 [95% CI 130-135]）的中位卒中风险和中位收缩压（SBP）分别显著高于幸存者。每周体育锻炼时间超过 2.5 小时的人从 COVID-19 中存活的几率要高出 3.1 倍。每天饮酒超过一杯标准酒精饮料、患有心房颤动或记忆力差的人从 COVID-19 中死亡的几率分别是前者的 2.5 倍、2.3 倍和 2.6 倍：结论：中风高风险、缺乏运动、酒精摄入、高 SBP 和心房颤动与 COVID-19 的严重程度和死亡率有关。我们的研究结果表明，"中风风险计 "应用程序可作为 COVID-19 严重程度和死亡率的简单预测工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cerebrovascular Diseases Extra PERIPHERAL VASCULAR DISEASE-

CiteScore

3.50

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： This open access and online-only journal publishes original articles covering the entire spectrum of stroke and cerebrovascular research, drawing from a variety of specialties such as neurology, internal medicine, surgery, radiology, epidemiology, cardiology, hematology, psychology and rehabilitation. Offering an international forum, it meets the growing need for sophisticated, up-to-date scientific information on clinical data, diagnostic testing, and therapeutic issues. The journal publishes original contributions, reviews of selected topics as well as clinical investigative studies. All aspects related to clinical advances are considered, while purely experimental work appears only if directly relevant to clinical issues. Cerebrovascular Diseases Extra provides additional contents based on reviewed and accepted submissions to the main journal Cerebrovascular Diseases.