The Debulking of Recurrent Right Testicular Seminoma with Anterolateral Thigh Flap Reconstruction

S. Fadhly, Rachmat Budi Santoso, Edward Usfie Harahap, Dewi Aisiyah Mukarramah, Kasih Rahardjo Djarot, I. A. Bramono, R. Rosalina, K. Kardinah, R. I. Putri
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Abstract

Introduction: Radical orchidectomy is considered both a therapy and a part of the staging procedure. Stage I seminoma may be treated with orchiectomy alone while the remaining 15% to 20% may have a relapse if they receive no additional treatment during the five-year surveillance. Most recurrences occur within the first 2 years after diagnosis, and the location of the recurrence is typically in the retroperitoneum. This article aims to share the experience in the management of testicular seminoma recurrence in a multidisciplinary approach.Case Presentation: We are reporting a case of a 26-year-old male with a growing mass at the right scrotum just two months after right radical orchidectomy. This patient was previously treated with a stage I seminoma and underwent surveillance. Tumor debulking and right inguinoscrotal reconstruction using a pedicled anterolateral thigh (ALT) flap were done through collaborative surgery between urology and plastic surgery. However, according to National Comprehensive Cancer Network (NCCN), with the relapsed mass, this patient can be classified as having a stage III seminoma and considered as having a good-risk disease due to no evidence of non-pulmonary visceral metastasis. With the risk of bleomycin causing lung fibrosis, four cycles of etoposide and cisplatin can be considered the chemotherapy regimens for this patient. Evaluation after chemotherapy should be done by checking tumor markers and imaging studies.Conclusions: The reappearance of testicular seminoma in this patient unexpectedly occurred quite in a short period, that is in two months after surgery. Immediate multidisciplinary intervention by a urologist and plastic surgeon was done through tumor debulking with a wide incision margin and ALT flap reconstruction. Unfortunately, however, after the second month of follow-up, there was a bulging mass growing beneath the flap which needed further evaluation with ultrasonography to confirm the possibility of tumor recurrence or seroma. If tumor recurrence is confirmed, chemotherapy should be scheduled as soon as possible.
股前外侧皮瓣再造治疗复发性右睾丸精原细胞瘤
简介:根治性睾丸切除术被认为是一种治疗方法和分期程序的一部分。一期精原细胞瘤可单独用睾丸切除术治疗,其余15%至20%的患者如果在5年的监测期间没有接受额外治疗,可能会复发。大多数复发发生在诊断后的头2年内,复发的位置通常在腹膜后。本文旨在分享多学科方法治疗睾丸精原细胞瘤复发的经验。病例介绍:我们报告一例26岁的男性在右侧根治性睾丸切除术后两个月右侧阴囊出现肿块。该患者曾接受I期精原细胞瘤治疗并接受监测。通过泌尿外科和整形外科的联合手术,应用带蒂股前外侧皮瓣行右侧腹股沟肿瘤切除和腹股沟阴囊重建。然而,根据国家综合癌症网络(NCCN),对于复发的肿块,由于没有证据表明非肺部内脏转移,该患者可归类为III期精原细胞瘤,并被认为是高风险疾病。考虑到博来霉素引起肺纤维化的风险,可以考虑对该患者进行依托泊苷和顺铂四个周期的化疗方案。化疗后的评估应通过检查肿瘤标志物和影像学检查来完成。结论:该患者的睾丸精原细胞瘤在术后2个月的时间内意外复发。泌尿科医生和整形外科医生立即进行多学科干预,通过宽切口切除肿瘤和ALT皮瓣重建。然而,不幸的是,随访第二个月后,皮瓣下出现膨出肿块,需要进一步超声检查以确认肿瘤复发或血清肿的可能性。如果确认肿瘤复发,应尽快安排化疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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