(2S*,5S*,6Z)-2,5-Epoxydocosan-6-en-21-ynoic Acid, New Fatty Acid from the Marine Sponge Haliclona fascigera

P. Campos, E. Pichon, B. Illien, P. Clerc, C. Moriou, N. Voogd, C. Hellio, R. Trépos, M. Frédérich, A. Al‐Mourabit, A. Gauvin-Bialecki
{"title":"(2S*,5S*,6Z)-2,5-Epoxydocosan-6-en-21-ynoic Acid, New Fatty Acid from the Marine Sponge Haliclona fascigera","authors":"P. Campos, E. Pichon, B. Illien, P. Clerc, C. Moriou, N. Voogd, C. Hellio, R. Trépos, M. Frédérich, A. Al‐Mourabit, A. Gauvin-Bialecki","doi":"10.4172/2329-6836.1000336","DOIUrl":null,"url":null,"abstract":"Marine sponges are recognized as a rich source of new marine natural products. In this study, chemical investigation of the CH2Cl2-MeOH (1:1) extract from the marine sponge Haliclona fascigera collected in Mayotte was carried out and highlighted a new unusual acetylenic and tetrahydrofuranic fatty acid, (2S*,5S*,6Z)-2,5epoxydocosan-6-en-21-ynoic acid (1). Its planar structure was elucidated by HRESIMS data, IR, 1D and 2D NMR spectra. The relative configuration of compound 1 was deduced from density functional theory (DFT) computational calculations fitted using the recently published DP4+ probability.","PeriodicalId":18897,"journal":{"name":"Natural products chemistry & research","volume":"44 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural products chemistry & research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2329-6836.1000336","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3

Abstract

Marine sponges are recognized as a rich source of new marine natural products. In this study, chemical investigation of the CH2Cl2-MeOH (1:1) extract from the marine sponge Haliclona fascigera collected in Mayotte was carried out and highlighted a new unusual acetylenic and tetrahydrofuranic fatty acid, (2S*,5S*,6Z)-2,5epoxydocosan-6-en-21-ynoic acid (1). Its planar structure was elucidated by HRESIMS data, IR, 1D and 2D NMR spectra. The relative configuration of compound 1 was deduced from density functional theory (DFT) computational calculations fitted using the recently published DP4+ probability.
(2S*,5S*,6Z)-2,5-环氧多聚糖-6-烯-21-乙烯酸,海绵体新脂肪酸
海洋海绵被认为是新的海洋天然产品的丰富来源。本研究对采自马约特岛的海绵状海绵(Haliclona fascigera)的CH2Cl2-MeOH(1:1)提取物进行了化学研究,发现了一种新的不常见的乙炔和四氢呋喃脂肪酸(2S*,5S*,6Z)- 2,5epoxydocosan6 -en-21-ynoic酸(1)。通过HRESIMS数据、IR、1D和2D NMR对其平面结构进行了表征。化合物1的相对构型由密度泛函理论(DFT)计算推导,该计算采用最近发表的DP4+概率拟合。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信