Role of Flavonoids against COVID-19

A. Fatima, Y. Siddique
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Abstract

The novel coronavirus disease (COVID-19) has entered a threatening stage all over the world. Many lives have been lost, and many more are in need of treatment. The mild symptoms may include fever and dry cough, but in severe cases, it could lead to pneumonia and ultimately death in some instances. Though medical scientists all over the globe are working hard to develop a treatment for this disease, yet no definite cure has been found. To date, the treatment strategy is based on adopting strategies to break the transmission of the virus and repurposing of the old drugs to prevent the loss of life. Among the various potent candidates, flavonoids may play a protective role in these times. Studies have already proven various health-promoting properties of flavonoids in earlier viral diseases, like SARS and MERS. Since ancient times, been plants have used to treat a number of human diseases. Different phytoproducts have been previously described to inhibit the replication of numerous viruses. Despite the positive reports for plant-based medications, no successful clinical trials on phytoproducts as anti-COVID agents have been conducted to date. This review highlights the efficacy of flavonoids as a treatment strategy either alone or in combination with other drugs.
类黄酮抗COVID-19的作用
新型冠状病毒病(COVID-19)在全球范围内已进入威胁阶段。许多人失去了生命,还有更多的人需要治疗。轻微的症状可能包括发烧和干咳,但在严重的情况下,它可能导致肺炎,在某些情况下最终导致死亡。虽然全世界的医学科学家都在努力研究治疗这种疾病的方法,但还没有找到确切的治愈方法。迄今为止,治疗战略的基础是采取阻断病毒传播和重新利用旧药物以防止生命损失的战略。在各种有效的候选物质中,类黄酮可能在这些时候起保护作用。研究已经证明,黄酮类化合物在早期病毒性疾病(如SARS和MERS)中具有多种促进健康的特性。自古以来,植物就被用来治疗许多人类疾病。不同的植物产品先前已被描述为抑制许多病毒的复制。尽管基于植物的药物有积极的报道,但迄今为止还没有成功的植物产品作为抗covid药物的临床试验。这篇综述强调了黄酮类化合物作为单独或与其他药物联合治疗策略的有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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