COVID-19 as a cause of acute kidney transplant rejection: clinical and morphological analysis of a fatal case report

Abstract

COVID-19 against the background of the respiratory system damage often causes changes in the morpho-functional state of the kidneys, accelerates the progression and development of complications of chronic kidney disease, and is the cause of a high mortality rate in kidney transplant recipients. In the article, the authors conduct a detailed clinical and morphological analysis of a fatal case report of acute kidney transplant rejection of antibody-mediated and cell-mediated genesis, the development of which was determined by the presence of COVID-19 in the patient. The authors emphasize that the morphological study is crucial for the diagnosis of renal transplant rejection. This clinical and morphological analysis of a case report shows the need for an individual approach to this category of patients for the purpose of timely diagnosis, treatment and prevention of COVID-19.