MANAGEMENT OF ESSENTIAL HYPERTENSION USING HERBAL FORMULATION WITH AND WITHOUT GOKSHURA KWATHA – A COMPARATIVE STUDY

April 2021 Pub Date : 2021-05-16 DOI:10.46607/iamj0209042021

Pooja Gautam, R. Chaturvedi, Shraddha Sharma

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Abstract

Hypertension is one of the major causes of cardiovascular morbidity and mortality worldwide. It is a global health problem affecting the people of different ethnicity and ages around the world. An estimated 1.13 billion people worldwide have hypertension, most (two-thirds) living in low- and middle-income countries. According to WHO (2015) the overall prevalence of hypertension in India was 24.2% and 22% among the men and women respectively. Hypertension is called a silent killer, non-communicable chronic disease because it rarely exhibits symptoms before it damages vital organs like kidney, brain or heart. In Ayurveda there is not a single disease which resemble with hypertension, but physician should understand the disease through Dosha, Dushya, Samprapti and initiate the treatment. A lot of potent modern antihypertensive drugs are available but none of them are free from untoward side-effects. So, a clinical study was done using herbal formulation containing Sarpaghandha, Sankhpushpi, Arjuna, Jatamansi and Ashwagandha in the form of Ghanvati. A comparative study was done as this Ghanvati was given with and without Gokshur kwath. For clinical study 52 (Group A- 25 and Group B- 27) clinically diagnosed patients of essential hypertension who fulfil inclusion criteria were selected irrespective of their age, sex, religion, occupation etc. and simple random sampling technique was followed for grouping the patients into 2 groups. All the patients selected for the clinical trial were divided in two groups ‘A’ and ‘B’. Patients of Group A were given 250 mg of Ghanvati two times a day with water as Anupan and patients of Group B were given 250 mg of Ghanvati with water as Anupan and Gokshur kwath both two times a day. Duration of the study for each group was 30 days. The present study showed that herbal formulation is also effective in the management of essential hypertension. Keywords: Essential hypertension, Ghanvati

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用草药制剂治疗原发性高血压的比较研究

高血压是全世界心血管疾病发病和死亡的主要原因之一。这是一个全球性的健康问题，影响到世界各地不同种族和年龄的人。据估计，全世界有11.3亿人患有高血压，其中大多数(三分之二)生活在低收入和中等收入国家。根据世界卫生组织(2015年)的数据，印度男性和女性的高血压总体患病率分别为24.2%和22%。高血压被称为无声杀手，是一种非传染性慢性疾病，因为它在损害肾脏、大脑或心脏等重要器官之前很少表现出症状。在阿育吠陀中，没有一种疾病与高血压相似，但医生应该通过Dosha, Dushya, Samprapti了解这种疾病并开始治疗。现在有很多有效的现代降压药，但没有一种没有副作用。因此，一项临床研究使用了含有Sarpaghandha, Sankhpushpi, Arjuna, Jatamansi和Ashwagandha的草药配方，以ganvati的形式进行。做了一项比较研究，因为这个ganvati有和没有Gokshur kwath。临床研究选取符合入选标准的临床诊断的原发性高血压患者52例(A ~ 25组，B ~ 27组)，不考虑年龄、性别、宗教、职业等因素，采用简单随机抽样的方法将患者分为两组。所有入选临床试验的患者被分为A组和B组。A组患者给予250 mg Ghanvati，每天2次，加水作为Anupan; B组患者给予250 mg Ghanvati，加水作为Anupan和Gokshur kwath，每天2次。每组的研究时间为30天。本研究表明，中药制剂对原发性高血压的治疗也是有效的。关键词:原发性高血压;Ghanvati

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April 2021

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