{"title":"Audiological evaluation of the cochlear nerve with brainstem evoked response audiometry in patients with COVID-19.","authors":"A Taş, B Haznedar, M C Tuncer","doi":"10.12871/000398292022342","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>In this clinical study, it was aimed to prospectively evaluate the cochlear nerve with brainstem evoked response audiometry (BERA) in terms of audiological ailments in patients with COVID-19. Although the relationship of COVID-19 with tinnitus and hearing loss has been investigated since the day this infectious respiratory disease emerged, its relationship with BERA has not been fully demonstrated from a neurological perspective.</p><p><strong>Methods: </strong>It was carried out on a group of patients who had COVID-19 in the last 6 months between February and August 2021 in Diyarbakır Gazi Yaşargil Training and Research Hospital. Patients between the ages of 18-50, who applied to the otorhinolaryngology and neurology clinic and had COVID-19 in the last 6 months, were selected. The COVID-19 group of our study consisted of 30 patients, 18 males and 12 females, who had had COVID-19 disease in the last 6 months, and 30 healthy individuals, 16 males and 14 females, as the control group.</p><p><strong>Results: </strong>In patients with COVID-19, the evaluation of the destruction of the cochlear nerve with BERA showed that there was a statistically significant prolongation in I-III and I-V interpeaks at 70, 80 and 90 db nhl.</p><p><strong>Conclusions: </strong>Statistically significant prolongation of especially I-III and I-V Interpeaks in BERA showed that COVID-19 has the potential to cause neuropathy. We believe that the BERA test should be considered in the neurological evaluation of cochlear nerve damage in patients with COVID-19 as a differential diagnosis.</p>","PeriodicalId":55476,"journal":{"name":"Archives Italiennes De Biologie","volume":"160 3-4","pages":"106-114"},"PeriodicalIF":0.8000,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives Italiennes De Biologie","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.12871/000398292022342","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: In this clinical study, it was aimed to prospectively evaluate the cochlear nerve with brainstem evoked response audiometry (BERA) in terms of audiological ailments in patients with COVID-19. Although the relationship of COVID-19 with tinnitus and hearing loss has been investigated since the day this infectious respiratory disease emerged, its relationship with BERA has not been fully demonstrated from a neurological perspective.
Methods: It was carried out on a group of patients who had COVID-19 in the last 6 months between February and August 2021 in Diyarbakır Gazi Yaşargil Training and Research Hospital. Patients between the ages of 18-50, who applied to the otorhinolaryngology and neurology clinic and had COVID-19 in the last 6 months, were selected. The COVID-19 group of our study consisted of 30 patients, 18 males and 12 females, who had had COVID-19 disease in the last 6 months, and 30 healthy individuals, 16 males and 14 females, as the control group.
Results: In patients with COVID-19, the evaluation of the destruction of the cochlear nerve with BERA showed that there was a statistically significant prolongation in I-III and I-V interpeaks at 70, 80 and 90 db nhl.
Conclusions: Statistically significant prolongation of especially I-III and I-V Interpeaks in BERA showed that COVID-19 has the potential to cause neuropathy. We believe that the BERA test should be considered in the neurological evaluation of cochlear nerve damage in patients with COVID-19 as a differential diagnosis.
目的:在本临床研究中,采用脑干诱发反应听力学(BERA)技术对新冠肺炎患者听力学病变的耳蜗神经进行前瞻性评价。尽管自COVID-19这种传染性呼吸道疾病出现之日起就开始研究其与耳鸣和听力损失的关系,但其与BERA的关系尚未从神经学角度得到充分证实。方法:选取Diyarbakır Gazi ya argil培训与研究医院2021年2月至8月6个月内感染COVID-19的患者为研究对象。选择年龄在18-50岁之间,在最近6个月内就诊于耳鼻喉科和神经内科门诊并患有COVID-19的患者。本研究的COVID-19组包括最近6个月感染COVID-19的患者30例,男性18例,女性12例;对照组为30例健康个体,男性16例,女性14例。结果:在COVID-19患者中,BERA对耳蜗神经破坏的评估显示,在70、80、90 db nhl时,I-III、I-V间峰延长有统计学意义。结论:BERA的I-III和I-V峰间期延长具有统计学意义,表明新冠肺炎具有引起神经病变的潜力。我们认为,在COVID-19患者耳蜗神经损伤的神经学评估中,应考虑BERA试验作为鉴别诊断。
期刊介绍:
Archives Italiennes de Biologie - a Journal of Neuroscience- was founded in 1882 and represents one of the oldest neuroscience journals in the world. Archives publishes original contributions in all the fields of neuroscience, including neurophysiology, experimental neuroanatomy and electron microscopy, neurobiology, neurochemistry, molecular biology, genetics, functional brain imaging and behavioral science.
Archives Italiennes de Biologie also publishes monographic special issues that collect papers on a specific topic of interest in neuroscience as well as the proceedings of important scientific events.
Archives Italiennes de Biologie is published in 4 issues per year and is indexed in the major collections of biomedical journals, including Medline, PubMed, Current Contents, Excerpta Medica.