THE EFFECTIVENESS OF ANCHOVY INTAKE ON EPITHELIAL SOCKET THICKNESS POST EXTRACTION

T. Indriana, Agus Sumono, Kunti Sholihah
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Abstract

Background: Epithelial formation or re-epithelialization is one of the parameters in the wound closure. Nutrition has become a major factors in the successful outcome during this process. Anchovy ( Stolephorus sp. ) contains several proteins, vitamins, and minerals that can act as supplements to support wound closure. This research proposed to understand the effect of anchovy intake toward epithelial thickness of the rats post tooth extraction. Method: This research was an experimental laboratory with a post-test-only control group design using 24 rats as a sample. Rats were divided into 2 groups, the control and the treatment group with 12 rats each. The mandibular left first molar of the samples was extracted, then given with aquadest (the control) and anchovy powder (the treatment) during 3, 5, and 7 days. All rats were decapitated after 24 hours from the last treatment, followed by tissue processing and staining with Hematoxylin-Eosin (HE) for examination. A microscope that connects with optilab on a magnification of 100x was used to measure the epithelial thickness on the thickest and thinnest part of the epithelial. The data were analysed with One-way ANOVA test and LSD test. Result: The results showed that the epithelial thickness of the treatment group was significantly increased compared to the control group (p<0.05). Conclusion: This study concludes that the anchovy ( Stolephorus sp .) intake affects increasing epithelial socket thickness of the rats post tooth extraction.
凤尾鱼摄取量对提取后上皮窝厚度的影响
背景:上皮形成或再上皮化是伤口愈合的参数之一。在这一过程中,营养已成为成功结果的主要因素。凤尾鱼(Stolephorus sp.)含有几种蛋白质、维生素和矿物质,可以作为辅助伤口愈合的补充剂。本研究旨在了解凤尾鱼摄取量对大鼠拔牙后上皮细胞厚度的影响。方法:本研究以24只大鼠为样本,采用后验对照组设计。将大鼠分为对照组和治疗组,每组12只。提取样品的下颌左第一磨牙,分别于第3、5、7天给予aquadest(对照组)和鳀鱼粉(治疗组)。末次给药24小时后,取大鼠头颅,进行组织处理和苏木精-伊红(HE)染色。使用与optilab连接的显微镜,放大倍数为100倍,测量上皮最厚和最薄部分的上皮厚度。数据分析采用单因素方差分析和LSD检验。结果:与对照组相比,治疗组上皮细胞厚度显著增加(p<0.05)。结论:摄入凤尾鱼可增加拔牙后大鼠上皮窝厚度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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