Study of bleeding disorders (hemophilia) in children in Beni-Suef university hospital

Abstract

: The goal of this study is to study the clinical spectrum of hemophiliac children (age <18 years) in Beni-Suef university hospital. A cross-sectional study conducted in the pediatric hematology clinic of Beni-Suef university hospital, over a period of 12 months. Out of a total of 112 cases enrolled, 91% were diagnosed as hemophilia A. While (9%) were diagnosed as hemophilia B. Positive family history was found in (46%) of cases. The mean age of onset of symptoms and diagnosis was 1.7 ± 1.4 and 3.8 ± 3.8 years, respectively. ), the most common bleeding symptom was bruises (86.5), the most serious was intracranial hemorrhage (9.6%). While haemarthrosis was in (7.7%).Conclusion: Occurrence of posttraumatic bleeds and gum bleeds in an otherwise normal child should warn the clinician for evaluation of hemophilia. Hemophilias are distributed worldwide and have heterogeneous presentation depending upon the disease severity. Knowledge of the spectrum of presentation of hemophilia in the local population helps in early diagnosis and planning of management.