Comparative Study of Conventional and Transgastric Necrosectomy for WideExtended Walled-of Pancreatic Necrosis

Szentkereszty Zs, N. Krasnyánszky, A. Kammili, K. Balog, M. Berhés, Sápy P Gy
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Abstract

Purpose: Even though endoscopic necrosectomy for walled-off pancreatic necrosis is safe and effective, open surgery has an important role in cases with extended necrosis when the non-surgical approaches are not feasible. Authors compare their results of conventional and transgastric open necrosectomy. Methods: A total of 29 patients were treated with extended walled-off pancreatic necrosis. Conventional open necrosectomy with closed bursal lavage was performed in group A (18 patients) and transgastric necrosectomy was performed in group B (11 patients). There were no significant differences between the two groups related to sex, age, etiology of pancreatitis, size of WOPN and time elapsed from the onset of disease and surgery. Results: For all complications, the difference was significant between both groups (p=0.003). In group A, 13 reoperations were performed in 9 patients and none were required in group B. The difference between both groups was significant (p=0.01). The length of hospital stay was 23 ± 14.16 days in group A and 12 ± 2.2 days in group B. The difference was significant (p=0.001). The mortality in group A was higher than in group B (p=0.143), but it was not significant. The mean mortality rate was 13.8% in 29 patients. Conclusion: In patients with extended walled-off pancreatic necrosis, the open transgastric necrosectomy has better results than conventional necrosectomy.
常规与经胃切除术治疗大面积胰腺壁性坏死的比较研究
目的:尽管内窥镜下坏死切除术治疗壁闭塞性胰腺坏死是安全有效的,但在非手术方法不可行的扩展性坏死病例中,开放手术具有重要作用。作者比较了常规和经胃开放性坏死切除术的结果。方法:对29例扩大壁脱性胰腺坏死患者进行治疗。A组(18例)行常规开放性坏死切除术加封闭法囊灌洗术,B组(11例)行经胃坏死切除术。两组患者在性别、年龄、胰腺炎病因、WOPN大小、发病及手术时间等方面无显著差异。结果:两组在所有并发症方面差异均有统计学意义(p=0.003)。A组9例患者13例再手术,b组无再手术,两组比较差异有统计学意义(p=0.01)。A组住院时间为23±14.16 d, b组为12±2.2 d,差异有统计学意义(p=0.001)。A组病死率高于B组(p=0.143),但差异无统计学意义。29例患者平均死亡率为13.8%。结论:经胃切开胰腺坏死切除术治疗扩大壁脱性胰腺坏死的效果优于常规胰腺坏死切除术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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