[Secondary diabetes].

K. Tsuda, Y. Seino
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Abstract

Secondary diabetes may occur in association with endocrine or nonendocrine disorders. The most common endocrine diseases associated with glucose intolerance are those involving the overproduction of counter regulatory hormones. Nonendocrine conditions associated with glucose intolerance or diabetes fall into three general categories: pancreatic diseases, drug-induced diabetes, and genetic syndromes. The therapy for secondary diabetes centers on the correction of an underlying disturbance. Patients with fasting hyperglycemia should be treated with an understanding of the pathophysiologic basis of their diabetes. in autoimmune diabetes (Type 1 diabetes and LADA Type diabetes), its etiopathogenesis is established and the primary disorder is pancreatic β-cell damage, and in Type 2 diabetes the primary cause is insulin resistance, in secondary diabetes, the etiopathogenesis of glucose homeostasis disorders is diverse and most often multifactorial.
(二次糖尿病)。
继发性糖尿病可能与内分泌或非内分泌疾病有关。与葡萄糖耐受不良相关的最常见的内分泌疾病是那些涉及反调节激素过量产生的疾病。与葡萄糖耐受不良或糖尿病相关的非内分泌疾病可分为三大类:胰腺疾病、药物性糖尿病和遗传综合征。继发性糖尿病的治疗以纠正潜在的障碍为中心。对空腹高血糖患者的治疗应了解其糖尿病的病理生理基础。在自身免疫性糖尿病(1型糖尿病和LADA型糖尿病)中,其发病机制是确定的,主要疾病是胰腺β细胞损伤,在2型糖尿病中,主要原因是胰岛素抵抗,在继发性糖尿病中,葡萄糖稳态紊乱的发病机制是多种多样的,最常是多因素的。
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