Study of seroprevalence of hepatitis a and e viruses in patients of acute viral hepatitis in a tertiary care centre in sub himalayan region

Indian Journal of Microbiology Research Pub Date : 2022-04-15 DOI:10.18231/j.ijmr.2022.004

P. Sharma, G. Sharma, A. Sharma, S. Verma, P. Panda, G. Sharma

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Abstract

Acute viral hepatitis is a systemic infection affecting the liver predominantly. It is common health problem in areas where safe drinking water is not universally available. In recent times we have witnessed frequent outbreaks as a result of that.: To estimate sero-positivity of Hepatitis A and E viruses in indoor patients of hepatitis, presenting with jaundice using ELISA.: Blood samples and clinical information were collected from cases of jaundice and referred to VRDL lab for analysis over a period of 1 year.: Samples were tested for anti –HAV immunoglobulin M (IgM) and anti –HEV immunoglobulin M (IgM).Data was entered into a pre-structured data entry form, on Microsoft Excel sheet.The viral etiology was confirmed in 236 (41.1%) cases while in 337 (58.8%) cases no hepatitis virus could be detected, hepatitis E virus were found to be maximum in 45.76% cases, followed by HAV (39.83% cases)and while in 14.41% cases no hepatitis virus could be detected.: Routine basic microbiological analysis of drinking water should be carried out by assaying the presence of Escherichia coli by the multiple tube fermentation technique.

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亚喜马拉雅地区三级保健中心急性病毒性肝炎患者甲型和戊型肝炎病毒血清流行率的研究

急性病毒性肝炎是一种以肝脏为主的全身性感染。在不能普遍获得安全饮用水的地区，这是一个常见的健康问题。最近，我们目睹了因此而频繁爆发的疫情。目的:应用酶联免疫吸附试验(ELISA)测定室内黄疸肝炎患者甲肝和戊肝病毒的血清阳性率。收集黄疸患者的血液样本和临床资料，并送交VRDL实验室进行分析，为期1年。:对样品进行抗甲型肝炎免疫球蛋白M (IgM)和抗hev免疫球蛋白M (IgM)检测。数据被输入到一个预先结构化的数据输入表单，在微软Excel表格上。确诊病例236例(41.1%)，未检出肝炎病毒337例(58.8%)，其中戊型肝炎病毒最多(45.76%)，甲肝病毒次之(39.83%)，未检出肝炎病毒14.41%。:饮用水常规基础微生物分析应采用多管发酵法检测大肠杆菌的存在。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Indian Journal of Microbiology Research

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