UV-Vis Spektrofotometrisi ile Geleneksel Bitkisel Ürünlerde (Jamu) Tıbbi Kimyasalların Doğrulanması

Q4 Pharmacology, Toxicology and Pharmaceutics
Fadli Husain, Ysrafil Ysrafi̇l, Rizka Pusji Astuti Daud, Andi Nur Aisyah, Alfat Fadri, Syamsu Nur
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引用次数: 0

Abstract

Traditional medicine "Jamu" is becoming very popular used by the community as an alternative treatment that can minimize side effects. However, it is profitable for manufacturers who are not responsible for herbal products by adding medicinal chemicals (BKO) to traditional herbal products. The samples used in this study were samples of traditional herbal medicine coded A1, A2; B1, B2; C1, C2; D1, D2; E1, E2; and F1, F2, which were analyzed qualitatively and quantitatively using thin-layer chromatography (TLC) and UV-Vis spectrophotometry. Based on the results obtained from the analysis using the TLC method, the herbal samples with code A1 A2 had a staining profile, Rf value, and chromatographic peak that were almost the same as the comparison standard for sodium metamizole with levels of 51.99% (A1) and 53.06% (B). the herbal medicine samples with codes B1, B2, and C1, C2 had stain profiles, Rf values, and spectrophotometric chromatography peaks that were almost the same as the comparison standard for paracetamol with paracetamol levels contained in the “Jamu” samples of 81.31% (B1), 81.66% (B2), 89.59% (C1) and 81.62% (C2). The results obtained from this study can be concluded that the samples of traditional herbal products with codes A1 and A2 contain sodium metamizole with levels of >50%. Samples of traditional herbal products B1, B2, C1, and C2 contain paracetamol with paracetamol levels contained > 50%, while the traditional herbal medicine samples with codes D1, D2, E1, E2, F1, and F2 have been identified as containing no medicinal chemicals in the traditional herbal medicine samples.
传统医学“Jamu”作为一种可以将副作用降到最低的替代疗法,在社区中越来越受欢迎。然而,对于不负责草药产品的制造商来说,在传统草药产品中添加药用化学品(BKO)是有利可图的。本研究使用的样品为编码为A1、A2的传统中草药样品;B1、B2;C1, C2;D1, D2;E1, E2;F1, F2,分别用薄层色谱法和紫外可见分光光度法进行定性和定量分析。薄层色谱法分析结果显示,编码A1 - A2的药材样品的染色谱、Rf值和色谱峰与对照标准物甲硝唑钠的含量基本一致,分别为51.99% (A1)和53.06% (B),编码B1、B2和C1、C2的药材样品的染色谱、Rf值和色谱峰与对照标准物甲硝唑钠的含量基本一致。“Jamu”样品中对乙酰氨基酚的含量分别为81.31% (B1)、81.66% (B2)、89.59% (C1)和81.62% (C2),其色谱峰与对照标准基本一致。本研究结果表明,编码为A1和A2的传统中草药产品样品中含有甲硝唑钠,含量>50%。传统中草药产品B1、B2、C1、C2样品中含有扑热息痛,扑热息痛含量> 50%,而编码为D1、D2、E1、E2、F1、F2的传统中草药样品经鉴定不含药用化学物质。
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来源期刊
Hacettepe University Journal of the Faculty of Pharmacy
Hacettepe University Journal of the Faculty of Pharmacy Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
CiteScore
0.60
自引率
0.00%
发文量
18
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