Dyslipidemia and Conventional Risk Factors in Patients with Acute Coronary Syndrome Admitted in a CCU of a Tertiary Care Hospital of Bangladesh

Cardiovascular Journal Pub Date : 2021-09-15 DOI:10.3329/cardio.v14i1.55370

Md Mahfuzur Rahman, F. Ahmed, S. Sharmin, T. Hyder, Saifuddin Nehal

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Abstract

Background: Coronary artery disease (CAD) is the single largest cause of death in the developed countries and is one of the leading causes of disease burden in developing countries. The prevalence of dyslipidemia and conventional risk factors profile at the time of admission in patients with Acute Coronary Syndrome (ACS) is not well described in our context. The aim of this study was to investigate the prevalence of dyslipidemia and conventional risk factors profiles of patients with ACS in a tertiary care center of Bangladesh. Methods: This descriptive cross-sectional study included 96 admitted patients of ACS [30 cases of Unstable Angina, 25 cases of Non ST segment Elevation Myocardial Infarction and 41 cases of ST segment Elevation Myocardial Infarction] from the Department of Cardiology, Abdul Malek Ukil Medical College Hospital, Noakhali, Bangladesh from January 2019 to June 2019. Fasting serum lipid profile was obtained within 24 hours of hospitalization and demographic and other cardiovascular risk factors were documented. Results: The mean age of the subjects were 57.7±14.4 years with majority (71.9%) being male. The most frequent reported risk factor was smoking, present in 55.2% of patients, followed by hypertension (47.9%), diabetes (37.5%), dyslipidemia (27.1%) and family history of CAD (15.6%). Based on Body Mass index 50% patients were obese (≥25kg/m2) and 69.8% had central obesity based on waist circumference. The lipid profile analysis revealed that 99% of patients had some type of dyslipidemia, and the most frequent was high level of triglyceride and low levels of high-density lipoprotein cholesterol (68.8% of cases in each). Conclusion: Dyslipidemia is a significant risk factor in patients with ACS and high TG and low HDL-C were more prevalent. Careful attention to its management may help to reduce further events. Cardiovasc j 2021; 14(1): 24-29

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孟加拉国一家三级医院CCU收治的急性冠状动脉综合征患者的血脂异常和常规危险因素

背景:冠状动脉疾病(CAD)是发达国家最大的单一死亡原因，也是发展中国家疾病负担的主要原因之一。在我们的研究中，急性冠脉综合征(ACS)患者入院时血脂异常的患病率和常规危险因素并没有得到很好的描述。本研究的目的是调查孟加拉国三级保健中心ACS患者的血脂异常患病率和常规危险因素概况。方法:本描述性横断面研究纳入2019年1月至2019年6月在孟加拉国Noakhali Abdul Malek Ukil医学院医院心内科住院的96例ACS患者[30例不稳定型心绞痛，25例非ST段抬高型心肌梗死，41例ST段抬高型心肌梗死]。在住院24小时内获得空腹血脂，并记录人口统计学和其他心血管危险因素。结果:患者平均年龄57.7±14.4岁，男性居多(71.9%)。最常见的危险因素是吸烟，占55.2%，其次是高血压(47.9%)、糖尿病(37.5%)、血脂异常(27.1%)和CAD家族史(15.6%)。根据体重指数，50%的患者为肥胖(≥25kg/m2)，根据腰围，69.8%的患者为中心性肥胖。脂质分析显示，99%的患者有某种类型的血脂异常，最常见的是高水平的甘油三酯和低水平的高密度脂蛋白胆固醇(每种病例的68.8%)。结论:血脂异常是ACS患者的重要危险因素，高TG和低HDL-C更为普遍。对其管理的仔细关注可能有助于减少进一步的事件。心血管病杂志2021;14 (1): 24-29

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Cardiovascular Journal

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