Comparison of Pharmaceutical Properties of Dextran Sulfate Sodium Tablets

Abstract

Fourteen brands of dextran sulfate sodium (DS-Na) tablets of 11 manufacturers (7 brands in sugar-coated tablet and remaining 7 in film-coated tablet) were tested on their pharmaceutical characteristics, heat resistance, moisture resistance and disintegration. In theheat resistance test, 9 brands out of the 14 showed “good” result, while 11 brands were proved “good” in moisture resistance. In the disintegration test after storage, 11 brands underwent no change.