BENEFICIAL EFFECTS OF GREEN TEA ON EXPERIMENTAL

Arun Kumar, V. Juyal
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Abstract

The present study was undertaken to investigate the beneficial effects of green tea in cognitive dysfunctions of mice. Memory impairment was produced by high fat diet (HFD). Morris water maze, elevated plus maze and passive avoidance test were employed to assess learning and memory. HFD significantly impair the learning and memory in mice. Furthermore HFD significantly increase serum nitrite and cholesterol concentrations. Pretreatment of green tea significantly reversed HFD induced learning and memory deficits along with attenuation of HFD-induced rise in serum nitrite and cholesterol concentrations.
绿茶对实验的有益作用
本研究旨在探讨绿茶对小鼠认知功能障碍的有益作用。高脂饮食(HFD)引起记忆障碍。采用Morris水迷宫、高架迷宫和被动回避测验评估学习记忆能力。HFD显著损害小鼠的学习和记忆能力。此外,HFD显著提高血清亚硝酸盐和胆固醇浓度。绿茶预处理显著逆转HFD诱导的学习和记忆缺陷,同时降低HFD诱导的血清亚硝酸盐和胆固醇浓度升高。
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